Biochemical Applications of Nonlinear Optical Spectroscopy

Nonlinear optical spectroscopy is a powerful tool for studying biomolecular structures and cellular organelles. Written by an international panel of experts, this volume presents the most significant advances and future directions within this important field. It provides an understanding of the nonlinear optical response of complex molecules and reviews developments in ultrafast technology. In addition, the editor includes a theoretical analysis of nonlinear optical spectroscopies. Novel experimental approaches, such as spatial and temporal pulse shaping, are addressed as well as various nonlinear optical spectroscopic tools, including harmonics generation and Raman spectroscopy.

Vladislav Yakovlev

Structural Dynamics and Kinetics of Myoglobin-CO Binding: Lessons from Time-Resolved X-ray Diffraction and Four-Wave Mixing Spectroscopy. Using Two-Photon Fluorescence Microscopy to Study Chemical Phenomena in the Skin. Ultrafast Fluorescence Microscopes. Multicontrast Nonlinear Imaging Microscopy. Broadband Laser Source and Sensitive Detection Solutions for Coherent Anti-Stokes Raman Scattering Microscopy. Nonlinear Optical Microspectroscopy of Biochemical Interactions in Microfluidic Devices. Advanced Multiphoton and CARS* Microspectroscopy with Broadband Shaped Femtosecond Laser Pulses. Nonlinear Optical Imaging with Sub-10 fs Pulses. Imaging with Phase Sensitive Narrowband Nonlinear Microscopy. Biomolecular Imaging by Near-Field Nonlinear Spectroscopy and Microscopy.