Heat Shock Proteins and Immune Response

This volume summarizes recent progress concerning various facets of the fascinating liaison between heat shock proteins (hsp) and immunity. It considers in depth both the central functions of hsp in the immune response and their potent antigenicity.

List of Contents.- Basic Features of Heat Shock Proteins.- Heat Shock Proteins hsp60 and hsp70: Their Roles in Folding, Assembly, and Membrane Translocation of Proteins.- Response of Mammalian Cells to Metabolic Stress; Changes in Cell Physiology and Structure/Function of Stress Proteins.- Heat Shock Protein Genes and the Major Histocompatibility Complex.- Heat Shock Protein Functions Related to Immunity.- BiP-A Heat Shock Protein Involved in. Immunoglobulin Chain Assembly.- A Role for Heat Shock Proteins in Antigen Processing and Presentation.- Heat Shock Proteins and Inflammation.- Heat Shock Proteins as Antigens.- Stress-Induced Proteins in Immune Response to Cancer.- Heat Shock Proteins as Virulence Factors of Pathogens.- Heat Shock Proteins as Antigens of Bacterial and Parasitic Pathogens.- Stress Proteins, Autoimmunity, and Autoimmune Disease.- Gamma/Delta T Lymphocytes and Heat Shock Proteins.