Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement

Economic evaluation has become an essential component of clinical trial design to show that new treatments and technologies offer value to payers in various healthcare systems. Although many books exist that address the theoretical or practical aspects of cost-effectiveness analysis, this book differentiates itself from the competition by detailing

Iftekhar Khan is a statistician, health economics researcher and academic at University College London (University of London). He has been an applied statistician for over 15 years in clinical trials, having worked in pharmaceutical companies and academic clinical trials units. Iftekhar Khan has completed degrees in statistics and mathematics from King's College London, the University of Kent and the University of Cambridge, including a master's in health economics and a PhD in health economic modelling (University College London).

Introduction to Economic Evaluation. Health Economic Evaluation Concepts. Designing Cost-Effectiveness into a Clinical Trial. Analyzing Cost Data Collected in a Clinical Trial. Quality of Life in Economic Evaluation. Modelling in Economic Evaluation. Sensitivity Analyses. Sample Size and Value of Information for Cost-Effectiveness Trials. Mixed Treatment Comparisons, Evidence Synthesis. Cost-Effectiveness Analyses of Cancer Trials. The Reimbursement Environment. References. Bibliography. Index.