Pathophysiology - E-Book

Learn the what, how, and why of pathophysiology! With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 8th Edition helps you understand the most important and most complex pathophysiology concepts. This updated text includes more than 1,300 full-color illustrations and photographs to make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW chapter on obesity and nutritional disorders, along with expanded coverage of rare diseases and epigenetics. It's the most comprehensive and authoritative pathophysiology text available!
- The most comprehensive and authoritative pathophysiology text on the market provides unparalleled coverage of Pathophysiology content - Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes - more than in any other pathophysiology text - Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment - Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content - Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition - Algorithms and flowcharts of diseases and disorders make it easy for you to follow the sequential progression of disease processes - Additional What's New boxes highlight the most current research and clinical development - Nutrition and Disease boxes explain the link between concepts of health promotion and disease - Chapter summary reviews provide concise synopses of the main points of each chapter
- NEW! Chapter on obesity and nutritional disorders thoroughly covers these growing global concerns - NEW! Added coverage of rare diseases and epigenetics further explore genetic disease traits - NEW! Over 50 new or heavily revised illustrations visually highlight pathophysiology concepts - NEW! More than 30 new 3D animations on Evolve bring difficult concepts to life for a new perspective on disease processes

Professor Kathryn L. McCance works at the College of Nursing at University of Utah, Salt Lake City, UT, USA.

Part 1: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUESUnit I: THE CELL1. Cellular Biology2. Altered Cellular and Tissue Biology: Environmental Agents3. The Cellular Environment: Fluids and Electrolytes, Acids and BasesUnit II: GENES AND GENE-ENVIRONMENT INTERACTION4. Genes and Genetic Diseases5. Genes, Environment-Lifestyle, and Common Diseases6. Epigenetics and DiseaseUnit III: MECHANISMS OF SELF-DEFENSE7. Innate Immunity: Inflammation8. Adaptive Immunity9. Alterations in Immunity and Inflammation10. Infection11. Stress and DiseaseUnit IV. CELLULAR PROLIFERATION: CANCER12. Cancer Biology13. Cancer Epidemiology14. Cancer in ChildrenPart 2: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMSUnit V: THE NEUROLOGIC SYSTEM15. Structure and Function of the Neurologic System16. Pain, Temperature Regulation, Sleep, and Sensory Function17. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function18. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction19. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders20. Alterations of Neurologic Function in ChildrenUnit VI: THE ENDOCRINE SYSTEM21. Mechanisms of Hormonal Regulation22. Alterations of Hormonal Regulation23. Obesity and Disorders of NutritionUnit VII: THE REPRODUCTIVE SYSTEMS24. Structure and Function of the Reproductive Systems25. Alterations of the Female Reproductive System26. Alterations of the Male Reproductive System27. Sexually Transmitted InfectionsUnit VIII: THE HEMATOLOGIC SYSTEM 28. Structure and Function of the Hematologic System29. Alterations of Erythrocyte, Platelet, and Hemostatic Function30. Alterations of Leukocyte and Lymphoid Function31. Alterations of Hematologic Function in ChildrenUnit IX: THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS32. Structure and Function of the Cardiovascular and Lymphatic Systems33. Alterations of Cardiovascular Function34. Alterations of Cardiovascular Function in ChildrenUnit X: THE PULMONARY SYSTEM35. Structure and Function of the Pulmonary System36. Alterations of Pulmonary Function37. Alterations of Pulmonary Function in ChildrenUnit XI: THE RENAL AND UROLOGIC SYSTEMS38. Structure and Function of the Renal and Urologic Systems39. Alterations of Renal and Urinary Function40. Alterations of Renal and Urinary Tract Function in ChildrenUnit XII: THE DIGESTIVE SYSTEM41. Structure and Function of the Digestive System42. Alterations of Digestive Function43. Alterations of Digestive Function in ChildrenUnit XIII: THE MUSCULOSKELETAL SYSTEM44. Structure and Function of the Musculoskeletal System45. Alterations of Musculoskeletal Function46. Alterations of Musculoskeletal Function in ChildrenUnit XIV: THE INTEGUMENTARY SYSTEM47. Structure, Function, and Disorders of the Integument48. Alterations of the Integument in ChildrenUnit XV: MULTIPLE INTERACTING SYSTEMS49. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults50. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children