Ovarian Cancer

This volume is the first of a new series dedicated to the historical developments in topics that are central to gynecological cancers. The six essays on ovarian cancer included here provide context from the perspective of experts in the field, illustrating what is required for the development and realization of medical innovation: (i) time consuming, decades-long basic research of the tumor genome and cancer cell biology, which may then set the basis for dramatic accelerations of recent therapeutic options; and (ii) the diligent assessment and fine-tuning of surgical techniques and concepts of patient prehabilitation and rehabilitation.

Malte Renz, MD, PhD, is an Attending Physician in Gynecologic Oncology and Principal Investigator in the Department of Gynecology with Center for Oncological Surgery at the Charité Universitätsmedizin Berlin.

Preface Contributors 1 Early Detection of Ovarian Cancer: An Update Chae Young Han, Zhen Lu, Karen H. Lu, Jacob S. Bedia, Anna Lokshin, Karen S. Anderson, Charles W. Drescher, Steven Skates, and Robert C. Bast, Jr. 2 History of Cytoreductive Surgery in Ovarian Cancer Treatment Alex A. Francoeur, Robert Bristow, and Jill Tseng 3 Hereditary Breast and Ovarian Cancer: A Historical Perspective Payal D. Shah and Susan M. Domchek 4 History of PARP Inhibitors Malte Renz and Jonathan S. Berek 5 History and Current Role of Immunotherapy in Ovarian Cancer Treatment Stephanie Chow and Oliver Dorigo 6 The History and Current Role of Perioperative Care and Prehabilitation in Ovarian Cancer Marlene Misu Lee and Jalid Sehouli Index