Oxidative Damage & Repair

This book was inspired by the presentations delivered at the Oxidative Damage & Repair Symposium (November, 1990). The book is organized into 20 chapters which mirror the 20 session topics of the Oxidative Damage & Repair Symposium.

Section headings and selected papers: Preface, K J A Davies. Introduction: Oxidative damage & repair: introduction and overview. Oxidative Stress Genes and Proteins. Oxidative stress genes and proteins: fire alarms and fire extinguishers, M Ma & J W Eaton. Antioxidant Compounds. An antioxidant role for hemoglobin, C Giulivi & K J A Davies. Intracellular Generation of Free Radicals. Formation of reactive oxygen species associated with mitochondrial respiration, H Nohl. Spin Trapping and New Developments in EPR. Quantitation with spin trapping in vivo, K T Knecht & R P Mason. DNA Damage and Repair. Repair of oxidative DNA damage in mammalian cells, P W Doetsch. Free Radical Chemistry and Radiochemistry. Oxidative Modification of Lipoproteins in Atherosclerosis. Photooxidative Stress and Photodynamic Therapy. Protein Damage and Repair. Mechanisms of Ischemia/Reperfusion Injury. Metabolic Regulation in Oxidative Stress. Smog. Lipid Damage and Repair. Antioxidant Enzymes. Inflammation. The components of the respiratory burst of oxidase of human neutrophils, B M Babior. Antioxidant Therapy: Ischemia/Reperfusion, Burn/Trauma. Antioxidant potential of ace inhibitors, M Chopra et al. Cytochrome P-450 and Oxidative Stress. Cancer and Oxidative Stress. Active oxygen species in the promotion and suppression of tumour cell growth, R H Burdon et al. Transition Metals in Oxidative Stress. Catalysis of oxyradical reactions by iron complexes, W H Koppenol et al. Antioxidant Therapy: Rheumatoid Diseases, Diseases of the Eye. Rationale for antioxidant therapy of rheumatoid. Diseases. Index.