Risk Assessment of Chemicals: An Introduction

This book offers an introduction to risk assessment of chemicals and contains basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products, and at the workplace. It includes chapters on environmental chemistry, toxicology and ecotoxicology as well as information on data requirements, data estimation methodologies and intelligent testing strategies. Coverage describes the basic principles and methods of risk assessment in their legislative frameworks (EU, USA, Japan and Canada). This second edition reflects the progress and experience gained in the last decade and again aims at providing background and training material for a new generation of risk assessors.

General Introduction.- Emissions of Chemicals to The Environment.- Transport, Accumulation and Transformation Processes.- Environmental Exposure Assessment.- Human Exposure Assessement.- Toxicity Testing for Human Health Risk Assessment.- Ecotoxicological Effects.- Data:Needs, Availability, Sources and Evaluation.- Predicting Fate-Related Physicochemical Properties.- Predicting Toxicological and Ecotoxicological Endpoints.- Intelligent Testing Strategies.- The Management of Industrial Chemicals in the Eu.- The Management of Industrial Chemicals in the USA.- The Management of Industrial Chemicals in Japan.- The Assessment and Management of Industrial Chemicals in Canada.- The Oecd Chemicals Programme.