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The book describes the molecular and genetic development of the auditory system in the ear that connects fibers to the brainstem, midbrain, and cortex. Age related hearing loss is reviewed.
Bernd Fritzsch is a leading expert in the field of inner ear neuroembryology and evolution, with almost 40 years' experience. He has organized multiple conferences, published books, journal articles, has 300 PubMed indexed papers and over 25,000 citations. His contributions to the field are conceptual and provide testable hypothesis using novel techniques. Bernd's research aims at the development and maintenance of the aging neurosensory system of the ear and its connection to the brain. He was the DEO (Chair) of the Department of Biology at the University of Iowa from 2008 - 2016. He developed a viable conditional deletion of mouse model that expands on earlier embryonic work on neurotrophin function for the inner ear on neuron viability into the postnatal phase. His work on the molecular basis of neurosensory development and maintenance helps others by fine tuning their approach toward restoration of lost hair cells and neurons. He has been the Director of the University of Iowa Aging Mind and Brain Initiative as well as the Center on Aging from 2013-2019. His research could provide a better molecular understanding of the underlying aging brain molecular changes. His recently applied R01 will allow us to use fluorescent genes to study age dependent mice defects in the vestibular and cochlear connection and function.
Preface. Introduction. Defining novelty in the neurosensory system. Evolving mechanosensation for gravity and angular orientation, lateral line, and electroreception. Connecting a novel sensory input from the ear to the brain: how to make new neuronal networks and new connections of an auditory system. Defining the auditory system of tetrapods. Sound processing: boundaries for auditory signal processing revealed. The evolution of the auditory system as a blueprint for sensory expansions using established principles - evolving new or adding artificial senses to expand the perception of the world. Summary and conclusions
