Biotechnology Engineering

Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale offers a comprehensive guide on biotechnology engineering, focusing on transforming research and development into commercially viable industrial processes. The book addresses the needs of the market by providing structured chapters, practical methods, and real-world case studies. Readers will gain valuable insights into bioprocessing basics, scalable solutions, optimization techniques, and collaboration opportunities. The text also covers essential regulatory compliance information, bridging the gap between theoretical knowledge and practical applications.The book is a vital resource for academics, scientists, engineers, and professionals in bioprocess development. It includes detailed discussions, calculations, and case studies, modern bioreactors, and software tools used in the industry. Serving as a desktop reference, it effectively combines theory with real-world applications to support the development of bioprocesses on all scales.- Helps readers understand the practical approach involved in bioprocess developments- Includes calculations and case studies that are essential for independently scaling up bioprocesses, from Erlenmeyer flask studies to bioreactors- Provides insights into auditing requirements for the bioprocess industry

PART A: Cell culture and Kinetic study1. Culturing of microbial, animal and plant cells in lab scale2. Microbial growth and cell kinetics3. Design, optimization, and Inoculum development for culturing the cells4. Lab scale studies on Submerged Liquid Fermentation (SLF) and Solid State Fermentation (SSF) PART B: Bioreactor handling and operation5. Fundamental of Bioreactors and accessories6. Design Aspects and Aseptic Maintenance of Bioreactors 7. Cleaning Techniques for Bioreactors and Regulatory Standards8. Bioreactor sterilization techniques and equipment9. Standard Operating Procedures and Auditing in Bioprocess Industries10. Operation and control of Submerged Liquid Fermenters11. Operation and control of submerged solid fermenters12. Equipment for downstream Product Recovery and Purification13. Modern Reactors and Software Tools in Bioprocess DevelopmentPART C: Bioreactor Scale up aspects and case studies14. Scale-Up Rules and Reactor Accessories15. Scale-Up Strategies for Submerged Liquid Fermentation 16. Scale-Up Strategies for Solid State Fermentation17. Scale-Up Constraints from Lab Scale to Industrial ScalePART D: Bioproducts18. Commercial Bioproducts from Bioreactors19. Bioproducts from Fermentation and their Economic Impact20. Manufacturing Techniques for Bioproducts