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Industrial Process Scale-up: A Practical Innovation Guide from Idea to Commercial Implementation, Second Edition helps industrial process innovators in research, development and commercial start-ups assess the risks of commercial-scale implementation, also providing them with practical guidelines and methods to reduce the risks to acceptable levels. In addition, the book can be used in cooperation with industrial R&D people and academic researchers to shape open innovation programs, and in education as a reference book. This updated edition has the latest literature and has been expanded with a scale-up of pharmaceutical processes and their history in both academia and the process industries.
- Offers easily accessible, step-by-step and concise guidelines for industrial process scale-up- Explains each stage of the innovation funnel, from research, development, demonstration and commercial implementation for any process type and branch- Based on industrial experiences and practices that reduce the risks of commercial scale implementation of new processes to acceptable levels and reduce cost and time of process innovation
Dr. Jan Harmsen is currently Director of Harmsen Consultancy B.V. From 1996 to 2010 he was Principal Process Developer, Shell Technology Center Amsterdam. After thirty-three years of industrial experience in exploratory research, development, process design, and chemicals manufacturing, ir. Harmsen now successfully works as an independent consultant on innovation with sustainable development in view. He has published three books with Elsevier.
1. Industrial Scale up Content and Context2. Discovery Stage Evaluation3. Concept Stage4. Feasibility Stage5. Development Stage6. Scale-up from Existing Pilot Plant7. Implementation Stage8. Industrial Scale-Up Cases
