Micronutrients in Health and Disease, Second Edition

Increased oxidative stress due to the production of excessive amounts of free radicals along with the effects of chronic inflammation plays a major role in the initiation and progression of most chronic diseases. In addition, increased release of glutamate plays a central role in the pathogenesis of various disorders. This second edition of Micronutrients in Health and Disease proposes a novel concept that in order to simultaneously and optimally reduce oxidative stress, chronic inflammation, and glutamate, it is essential to increase levels of antioxidant enzymes as well as levels of dietary and endogenous antioxidant compounds at the same time. This is accomplished by activating the Nrf2 pathways and by increasing the levels of antioxidant compounds and B-vitamins through supplementation. This book proposes a mixture of micronutrients that achieves this above goal. The mixture of micronutrients together with modification in diet and lifestyle may reduce the risk of chronic diseases and in combination with standard care, may improve the management of these diseases. KEY FEATURES . Provides evidence in support of the idea that increased oxidative stress, chronic inflammation, and glutamate are involved in the pathogenesis of chronic diseases. . Contains three new chapters on Huntington's disease, Autism spectra, and Prion disease. . Discusses the role of microRNAs in the pathogenesis of chronic diseases. . Presents information on regulation of the expression of microRNAs by reactive oxygen species and antioxidants. Micronutrients in Health and Disease, Second Edition serves as a valuable resource for those seeking to promote healthy aging and prevent and improved management of chronic diseases.

Dr. Kedar N. Prasad obtained a Masters degree in Zoology from the University of Bihar, Ranchi, India, and a Ph.D. degree in Radiation Biology from the University of Iowa, Iowa City, in 1963. He received Post-doctoral training at the Brookhaven National Laboratory, Long Island. New York, and joined the Department of Radiology at the University of Colorado Health Sciences Center where he became Professor and Director for the Center for Vitamins and Cancer Research. He has published over 250 articles in peer-reviewed journals, and authored and edited 25 books in the area of radiation biology, nutrition and cancer, and nutrition and neurological diseases particularly Alzheimer's disease and Parkinson's disease. These articles were published in highly prestigious journals such as Science, Nature, and Proceedings of the National Academic of Sciences, USA. Dr Prasad has received several honors which include: Invitation by the Nobel Prize Committee to nominate a candidate for the Nobel Prize in Medicine for 1982; The 1999 Harold Harper Lecture at the meeting of the American College of Advancement in Medicine; An award for the best review of 1998-1999 on antioxidant and cancer; and 1999-2000 on antioxidants and Parkinson's disease by the American College of Nutrition. He was a Fellow of the American College of Nutrition, and served as a President of the International Society of Nutrition and Cancer, 1992-2000. In 2017, he was invited to become the member of The Royal Society of Medicine, London. Currently, he is Chief Scientific Officer of the Engage Global.

Preface Chapter 1 Basic Facts about Micronutrients Chapter 2 Basic Facts about Oxidative Stress, Inflammation, and the Immune System Chapter 3 Scientific Rationale of Current Trends in Clinical Studies of Micronutrients Chapter 4 Micronutrients in Healthy Aging and Age-Related Decline in Organ Functions Chapter 5 Role of Micronutrients in Prevention of Coronary Artery Disease and Improvement of the Standard Therapy Chapter 6 Micronutrients in Prevention and Improvement of the Standard Therapy in Diabetes Chapter 7 Micronutrients in Cancer Prevention Chapter 8 Micronutrients in Improvement of the Standard Therapy in Cancer Chapter 9 Micronutrients in the Prevention and Improvement of the Standard Therapy for Alzheimer's Disease Chapter 10 Micronutrients for the Prevention and Improvement of the Standard Therapy for Parkinson's Disease Chapter 11 Micronutrients in Prevention and Improvement of the Standard Therapy in Hearing Disorders Chapter 12 Micronutrients in Improvement of the Standard Therapy in Posttraumatic Stress Disorder (PTSD) Chapter 13 Micronutrients in Improvement of the Standard Therapy in Traumatic Brain Injury Chapter 14 Micronutrients in Prevention and Improvement of the Standard Therapy in HIV/AIDS Chapter 15 Improved Management of Autism Spectrum Disorder (ASD) by Micronutrients Chapter 16 Micronutrients in the Management of Prion Disease Chapter 17 Micronutrients for Improved Management of Huntington's Disease Chapter 18 Micronutrients in Protecting Against Late Adverse Health-Effects of Diagnostic Radiation Doses Chapter 19 Micronutrients in Protecting Against Lethal Doses of Ionizing Radiation Chapter 20 Micronutrients in Prevention and Improvement of the Standard Therapy in Arthritis Chapter 21 Misconceptions about the Functions and Value of Antioxidants in Health and Disease Chapter 22 Dietary Reference Intakes of Selected Micronutrients Conclusions Index

Navigation
Inhaltsverzeichnis mit Links