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Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry.OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material.
- Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties- Presents the clinical potential of octacalcium phosphate biomaterials- Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration
1. Octacalcium Phosphate Biomaterials - Past present and Future2. Octacalcium phosphate effects on the systematic and local factors that regulate bone cell activity3. Octacalcium phosphate and the Biomineralisation of bone, cellular interactions and their role in bone repair4. Octacalcium Phosphate bone replacement and drug delivery5. Dissolution and growth of Octacalcium Phosphate in the presence of tooth proteins6. The influence of sterilization on Octacalcium phosphate for clinical applications7. An osteoinductive biomaterial Octacalcium Phosphate and its mechanism for bone formation8. Novel scaffold composites containing Octacalcium Phosphate and their role in bone repair9. Synthesis methodologies options for large scale manufacture of Octacalcium Phosphate10. Biomimetic synthesis of calcium phosphate-based biomaterials for hard tissue regeneration11. Future analysis techniques to assess mechanical and physiological behavior of novel calcium phosphate materials including Octacalcium Phosphate - In-vivo human clinical model12. Octacalcium phosphate for implant coating13. Calcium phosphate-based bone graft substitutes and the special roles of Octacalcium phosphate materials14. Unique compositional and structural properties of OCP among calcium phosphate15. Octacalcium phosphate collagen composites and their clinical application