Enough

*THE INSTANT NEW YORK TIMES BESTSELLER*. For her entire adult life, Oprah Winfrey has struggled with her weight. She never thought in her lifetime, medicines would provide hope, health, and healing for people like her. But as her conversations with Dr. Ania Jastreboff from the Yale School of Medicine reveal, we've learned that having obesity is not a choice. It's not a question of willpower. Obesity is a disease. It's a question of biology, created by our bodies' need to survive and the environment we created and now live in. And it's treatable. The new medications can lower our body fat set point (our brain's 'Enough Point'), so that we lose weight without battling biology with willpower. Dr. Jastreboff describes strategies to optimise health and manage side effects all with the reassuring perspective of decades of experience treating patients with obesity and leading studies with these medications. Many of her patients say the 'food noise' that plagued them for years has evaporated. They describe a new freedom from intrusive, persistent and disruptive thoughts about food. With treatment they begin a journey of healing with self-compassion, devoid of the shame and blame they've endured from society for decades. Oprah says she's learned so much from Dr. Jastreboff about how, when it comes to weight, our bodies work with us - and also against us. How each of our struggles are different and each of our choices in living with obesity may also be different. Dr. Jastreboff's groundbreaking research offers a new way forward, not only for obesity treatment, but also for overall health, with significant implications for the prevention and reversal of hundreds of related diseases. As she demonstrates in this book, when science meets empathy, real healing becomes possible. Yes, there is a path to healing and leading the life you have always wanted, when your brain is reassured that you have 'enough.'

Oprah Winfrey is a global media leader, philanthropist, producer and actress. She has created an unparalleled connection with people around the world, making her one of the most respected and admired figures today. For 25 years, Winfrey was the host and producer of the award-winning talk show The Oprah Winfrey Show, where she entertained, enlightened and uplifted millions of viewers. In her role as Chairman and CEO of OWN: Oprah Winfrey Network, she guided her cable network to success, is the founder of O, The Oprah Magazine and digital site OprahDaily.com, and oversees Harpo Productions. In 1996, Oprah's Book Club launched, serving as a catalyst for the creation of book clubs around the world and millions of books sold across genres, with the 100th selection recently being named. Ania M. Jastreboff, MD, PhD, is the Harvey and Kate Cushing Professor of Medicine (Endocrinology) and Professor of Pediatrics (Pediatric Endocrinology) at Yale School of Medicine. A compassionate physician-scientist and founding director of the Yale Obesity Research Center (Y-Weight), Dr. Jastreboff is an international thought leader in the scientific development and clinical application of novel obesity medications revolutionizing the treatment of obesity.