Semiconducting Silicon Nanowires for Biomedical Applications

In its second, extensively revised second edition, Semiconducting Silicon Nanowires for Biomedical Applications reviews the fabrication, properties, and biomedical applications of this key material. The book begins by reviewing the basics of growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires. Attention then turns to use of these structures for tissue engineering and delivery applications, followed by detection and sensing. Reflecting the evolution of this multidisciplinary subject, several new key topics are highlighted, including our understanding of the cell-nanowire interface, latest advances in associated morphologies (including silicon nanoneedles and nanotubes for therapeutic delivery), and significantly, the status of silicon nanowire commercialization in biotechnology. Semiconducting Silicon Nanowires for Biomedical Applications is a comprehensive resource for biomaterials scientists who are focused on biosensors, drug delivery, and the next generation of nano-biotech platforms that require a detailed understanding of the cell-nanowire interface, along with researchers and developers in industry and academia who are concerned with nanoscale biomaterials, in particular electronically-responsive structures. - Reviews the growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires
- Describes silicon nanowires for tissue engineering and delivery applications, including cellular binding & internalization, tissue engineering scaffolds, mediated differentiation of stem cells, and silicon nanoneedles & nanotubes for delivery of small molecule / biologic-based therapeutics
- Highlights the use of silicon nanowires for detection and sensing
- Presents a detailed description of our current understanding of the cell-nanowire interface
- Covers the current status of commercial development of silicon nanowire-based platforms

Part I: Introduction to silicon nanowires for biomedical applications: Synthesis and fundamental properties1. Overview of semiconducting silicon nanowires for biomedical applications2. Growth and characterization of semiconducting silicon nanowires for biomedical applications3. Surface modification of semiconducting silicon nanowires for biosensing applications4. Biocompatibility of semiconducting silicon nanowires Part II: Silicon nanowires for delivery and tissue engineering applications5. Functional semiconducting silicon nanowires for cellular binding and internalization6. Functional semiconducting silicon nanowires and their composites as tissue scaffolds7. Mediated differentiation of stem cells by engineered semiconducting silicon nanowires8. Nanoneedles devices for biomedicine9. Therapeutic platforms based on silicon nanotubes10. Silicon nanowires as spatially-defined therapeutics Part III: Silicon nanowires for detection and sensing11. Semiconducting silicon nanowire array fabrication for high throughput screening in the biosciences12. Nanostructured silicon for biological modulation13. CMOS-compatible silicon nanowire field-effect transistors: Where nanotechnology pushes the limits in biosensing14. Silicon nanowire composites for biosensing and therapy Part IV: Future opportunities and challenges15. The competition: non-silicon nanowire/nanotube strategies in nanomedicine16. Commercialization of silicon nanowire-based biotechnologies