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This handbook explains the major goals of synthetic biology and presents technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of current areas of focus, the handbook explores the standardisation of classic molecular bioscience approaches, addresses the societal context and impacts of synthetic biology, discusses the use of legacy systems as tools for product development, examines the design and construction of de novo cells and genetic codes, and describes computational methods for designing genes and gene networks.
Darren N. Nesbeth earned his BSc in molecular biology from University College London (UCL), UK, and his PhD in molecular cell biology from Imperial College, London, UK. He did postdoctoral work on scale up of gene therapy at King's College London, UK; fundamental cell biology at Imperial College; and industrially applied cell engineering at UCL. In the UCL Department of Biochemical Engineering, he applies synthetic biology to address industrial challenges in manufacturing of biopharmaceuticals and fine chemicals.
Synthetic Biology: Culture and Bioethical Considerations. Synthetic Biology Standards and Methods of DNA Assembly. Standardised Genetic Output Measurement. Bacterial Cells as Engineered Chassis. Eukaryotae Synthetica: Synthetic Biology in Yeast, Microalgae, and Mammalian Cells. Synthetic Plants. Theory and Construction of Semi-Synthetic Minimal Cells. Design Tools for Synthetic Biology. New Genetic Codes.
