Translational Bioinformatics Applications in Healthcare

This book offers a detailed overview and concepts of translation bioinformatics (TBI), biological/clinical databases, clinical informatics, and pertinent real-case applications. It explains advancements, tools, techniques, and applications of TBI including IoT, toxin databases, medical image analysis including COVID-19 CT-images, and so forth.

Part I T ranslational Healthcare, Next-Generation Sequence Analysis, and Drug Repurposing Chapter 1 Translational Healthcare System through Bioinformatics....................3 Mrinal Kumar Sarma, Rina Ningthoujam, Manasa Kumar Panda, Punuri Jayasekhar Babu, Ankit Srivastava, Maohinikanti Das and Yengkhom Disco Singh Chapter 2 Next-Generation Sequence Analysis for Clinical Applications..........23 Agnik Haldar and Ajay Kumar Singh Chapter 3 Clinical Applications of Next-Generation Sequence Analysis in Acute Myelogenous Leukemia........................................................ 41 Fatima Nazish Khan, Shaban Ahmad and Khalid Raza Chapter 4 Translational Bioinformatics Methods for Drug Repurposing........... 67 Jyoti Rani, Urmi Bajpai and Srinivasan Ramachandran Part II Internet of Things, Viroinformatics, and Toxin Databases for Healthcare Applications Chapter 5 The Fundamentals and Potential of IoT for Bioinformatics and Healthcare.....................................................................................87 Reinaldo Padilha França, Ana Carolina Borges Monteiro, Rangel Arthur, and Yuzo Iano Chapter 6 Viroinformatics and Viral Diseases: A New Era of Interdisciplinary Science for a Thorough Apprehension of Virology...................................................................109 Kayenat Sheikh and Khalid Raza Chapter 7 Toxin Databases and Healthcare Applications.................................. 133 Sushmita Baishnab, Subrata Sinha, Arabinda Ghosh, Ashwani Sharma and Surabhi Johari Part III Medical Image Processing and Other Healthcare Applications Chapter 8 Lossless Medical Image Compression Using Hybrid Block-Based Algorithm for Telemedicine Application..................... 147 Lenin Fred A. and L. R. Jonisha Miriam Chapter 9 Improved FCM Based on Gaussian Kernel and Crow Search Optimization for ROI Extraction on Corona Virus Disease (COVID-19) CT Images.................................................................... 173 S. N. Kumar, Lenin Fred A., L. R. Jonisha Miriam, Ajay Kumar H. Parasuraman Padmanabhan, and Balázs Gulyás Chapter 10 Estimating the Effect of Social Distancing in the Progression Dynamics of COVID-19.................................................................... 193 Narender Kumar, Shweta Sankhwar and Ravins Dohare