Magnesium Alloys as Degradable Biomaterials

Magnesium Alloys as Degradable Biomaterials provides a comprehensive review of the biomedical applications of biodegradable magnesium and its alloys. Magnesium has seen increasing use in orthopedic and cardiovascular applications over the last decade, particularly for coronary stents and bone implants.
The book discusses the basic concepts of biodegradation mechanisms as well as strategies to control biodegradation mode and rate, microstructure, mechanical properties, corrosion resistance to body fluid, and in vitro and in vivo biocompatibility.
The recently developed representative magnesium alloy systems-such as Mg-Ca, Mg-Zn, Mg-Sr, Mg-Ag, Mg-Li, and Mg-RE-are reviewed and their special properties illustrated. Also discussed are the biodegradable magnesium alloys/aqueous solution interface theoretical model and potential application prototypes, such as for cardiology and orthopedic surgery products.
Challenges of transitioning biodegradable magnesium alloys from raw materials to semi-products to final medical devices are covered along with main findings of worldwide experimental studies. An ideal reference book for researchers in the-area of biodegradable metals, it presents the state of the art of magnesium alloys designed for biomedical applications.

Yufeng Zheng, PhD, is a professor at Peking University in Beijing, China and was an associate full professor at the Harbin Institute of Technology in China, where he received his PhD in materials science. His areas of special interest include the development of various new biomedical metallic materials. He served as a member of the editorial board of various journals including the Journal of Biomedical Materials Research-Part B: Applied Biomaterials, the Journal of Biomaterials and Tissue Engineering, Materials Letters, Intermetallics, the Journal of Materials Science & Technology, Frontiers of Materials Science, Acta Metallurgica Sinica, Progress in Natural Science: Materials International, and the Journal of Orthopaedic Translation. Dr. Zheng has authored or co-authored more than 330 peer-reviewed articles.

Introduction. Biodegradation Mechanism and Influencing Factors of Mg and Its Alloys. Novel Structure Design for Biodegradable Mg and Its Alloys. Surface Modification Techniques for Biodegradable Mg and Its Alloys. Mg with High Purity for Biomedical Application. Mg-Ca-Based Alloy Systems for Biomedical Applications. Mg-Zn-Based Alloy Systems for Biomedical Application. Mg-Sr-Based Alloy Systems for Biomedical Applications. Mg-Ag-Based Alloy System for Biomedical Applications. Mg-Li-Based Alloy Systems for Biomedical Applications. Mg-RE-Based Alloy Systems for Biomedical Application. Fabrication and Processing of Biodegradable Mg and Its Alloys: From Raw Materials to Final Medical Devices. Design of Biodegradable Mg Alloy Implants with Finite Element Analysis. In Vivo Testing of Biodegradable Mg Alloy Implants.