Antioxidants in Health and Disease

Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Edited by Antonis Zampelas is a professor at the Department of Food Science and Human Nutrition of the Agricultural University of Athens in Greece and at the Department of Nutrition and Health of the United Arab Emirates University. He earned his master's degree in food science from the University of Reading and a PhD in clinical nutrition from the University of Surrey in the UK. He worked as research fellow at the University of Surrey, as senior scientific officer at the Ministry of Agriculture Fisheries and Food in the UK, as assistant professor at the Department of Nutrition and Dietetics at Harokopio University and as president of the Hellenic Food Authority in Greece. Professor Zampelas's research interests are in the field of cardiovascular nutrition and include conducting intervention studies and developing nutritional educational programs for Greek school children to prevent childhood obesity. He is also the principal investigator of the Hellenic Nutrition and Health Examination Survey. He has held leadership positions at various professional associations and committees. He has written or contributed to more than 120 peer-reviewed publications in international scientific journals and is the coauthor of 20 textbook chapters. Renata Micha is research assistant professor in the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University; and the director of the Hellenic National Health and Nutrition Examination Survey (H-NHANES) in the Department of Food Science and Human Nutrition at Agricultural University of Athens. Dr. Micha is a registered clinical dietician, public health nutritionist, and epidemiologist whose research focuses on global diet assessment and surveillance, the effects of diet on chronic diseases, mainly cardiometabolic diseases, and on population strategies to improve diet. She received a degree in nutrition and dietetics from Harokopio University of Athens, G

THE INTEREST IN ANTIOXIDANTS: WHY AND HOW? Reactive Oxygen Species: Production, Regulation, and Essential Functions. Major Dietary Antioxidants and Their Food Sources. ANTIOXIDANTS IN HEALTH. In Pregnancy. Role of Antioxidants in Children's Growth and Development. Adulthood and Old Age. Smoking, Oxidative Stress, and Antioxidant Intake. Physical Exercise. ANTIOXIDANTS IN DISEASE: CHRONIC DISEASES. Coronary Heart Disease and Stroke. Diabetes. Cancer. ANTIOXIDANTS IN DISEASE: NEURODEGENERATIVE DISEASES. Antioxidants in Neurodegeneration-Truth or Myth? ANTIOXIDANTS IN DISEASE: INFLAMMATORY DISORDERS. Gastrointestinal Disorders. Antioxidants in Obesity and Inflammation. ANTIOXIDANTS IN DISEASE: IMMUNE SYSTEM. Modulation of Immune Response by Antioxidants. ANTIOXIDANTS IN DISEASE: HIV/AIDS. HIV/AIDS. ROLE OF HERBS. Role of Herbs and Spices-In Health and Longevity and in Disease. Index.