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Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement.In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney.
- Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair- Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation- Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research- Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function
PART I: Kidney TransplantationSection I: Epidemiology of kidney disease and transplantationSection II: Donor selection and allocationSection III: Kidney preservation and transplant proceduresSection IV: Kidney recipients and transplantSection V: Transplantation immunology and immunomodulationSection VI: Graft monitoring toolsSection VII: Post-transplant immune eventsSection VIII: Early and late complicationsSection IX: Long-term outcomesSection X: Transplant issues and specific patientsSection XI: Ethics and costsSection XII: Unmet needsPART II: Kidney Bioengineering and RepairSection I: IntroductionSection II: BioengineeringSection III: Bioreactors and biomaterialsSection IV: RegenerationSection V: Adult cells for regenerationSection VI: Cell therapy for renal tissue repairSection VII: Future Perspectives