L-Arginine in Clinical Nutrition

Thistext presents the application of current nutritional knowledge by physiciansand dietitians and incorporates emerging fields of science and importantdiscoveries. It contains seven major sections.Section 1: Basic Processes at the Cellular Levels, Section 2: ArginineMetabolism and Functions, Section 3: Arginine Status in Cells Related to OrganDamage and Disease, Section 4: Arginine Status and Use in Healthy Individuals, Section5: Arginine and Diseases of the Gastrointestinal Tract, Section 6: Therapeuticuses of Arginine: Diabetes, Obesity and Cardiovascular Diseases and Section 7: Therapeutic Uses of Arginine: Cancer, WoundHealing and Infectious Disease.
Writtenby authors of international and national standing, leaders in the field andtrendsetters, Arginine in Clinical Nutrition is essential reading fornutritionists and dietitians, public health scientists, doctors,epidemiologists, health care professionals of various disciplines, policymakers and marketing and economic strategists.

Vinood B. Patel, BSc, PhD, FRSC
University of Westminster
Faculty of Science & Technology
Department of Biomedical Sciences
London, United Kingdom
Victor R. Preedy, BSc, PhD, DSc
Professor
King's College London
Dept Nutrition and Dietetics, Nutritional Sciences Division
School of Biomedical & Health Sciences, Franklin-Wilkins Building
London, United Kingdom
Rajkumar Rajendram, AKC, BSc (Hons), MBBS (Dist), MRCP (UK), FRCA, EDIC, FFICM Nutritional Sciences Research Division Faculty of Life Science and Medicine King's College London Franklin-Wilkins Building London, United Kingdom

Section 1: Basic Processes at theCellular Levels Chapter1 - Arginine uptake by cells - Geoffrey P. Candy and Marietha J. Nel Chapter2 - L-arginine and the expression of HSP70 and p-53 proteins - AgnieszkaPedrycz and Victor R. Preedy Chapter3 - AMP-activated protein kinase and L-arginine - SrinidiMohan Chapter4 - Amidine-based compounds affecting arginine metabolism - CristinaMaccallini, Marialuigia Fantacuzzi and Rosa Amoroso Chapter5 - Oxy- and sulfoanalogues of L-arginine - Tatyana Dzimbova and TamaraPajpanova Chapter6 - Regulation of expression and activity of L-arginine transporters bynutrients and hormones: A focus in transcriptional mechanisms regulated byglucose and insulin - Marcelo González Chapter7 - Arginine, pancreatic beta cellfunction and diabetes: mechanisms of stimulated insulin release and pathways ofmetabolism - Philip Newsholme, Kevin N. Keane, Mina Elahy and Vinicius Fernandes Cruzat Chapter 8 - Erythrocytes by-products of argininecatabolism - Martha Lucinda Contreras-Zentella and Rolando Hernández-Muñoz                                                                                 Section 2: Arginine Metabolismand Functions Chapter9 - Arginine synthesis from enteral proline - Christopher Tomlinson, RonaldO. Ball and Paul B. Pencharz Chapter10 - Arginine and macrophages: role in classical and alternative activation - JorgeLloberas, Manuel Modolell and Antonio Celada Chapter 11 - Arginine and TNF alphaproduction in macrophages: a focus on metabolism, ageing, metabolic syndromeand type 2 diabetes- CharlotteBreuillard, Christophe Moinard and Marie-Chantal Farges Chapter 12 - Arginine metabolism impairment during sepsisand diseases: causes and consequences - ChristopheMoinard, Charlotte Breuillard and Christine Charrueau  Chapter13 - Use of arginine with Growth Hormone Releasing Hormone (GHRH) and theendocrine response - Giulia Brigante and Vincenzo Rochira Chapter14 - Serum arginase in healthy subjects and nitric oxide - Keiki Ogino and KeiTakemoto                                       Section 3: Arginine Status inCells Related to Organ Damage and Disease Chapter15 - Protein Arginine Methylation ofRNA-binding Proteins and Their Impact on Human Diseases - Michael C. Yu andChristopher A. Jackson Chapter16 - DNA-arginine adducts and implications in disease - Haseeb Ahsan                         Chapter17 - Homoarginine and L-arginine: Glycine amidinotransferase in stroke - Chi-unChoe, Edzard Schwedhelm and Dorothee Atzler Chapter18 - The L-arginine/asymmetric dimethylarginine (ADMA) ratio in health anddisease: an overview - Murat Celik and Hilmi Umut Unal Chapter19 - Arginine and its transporters in colorectal cancer - Bingguan Chen, WeiminWang, Kang Ding, Junchen Wang, Peng Gao, Guowang Xu and Hai Hu Chapter20 - Arginine Uptake and Its Role in the Survival of Breast Cancer Cells -Catherine K. L. Too and Salma A. Abdelmagid             Section 4: Arginine Status and Usein Healthy Individuals                                                                                                 Chapter21 - Arginine production during pregnancy - Farook Jahoor, Jean W. Hsu,Pratibha Dwarkanath, Minerva M. Thame and Anura V. Kurpad Chapter22 - L-arginine in the uterus and placenta and during gestation in mammals -Jonathan M. Greene and Peter L. Ryan             Chapter23 - Oral L-arginine supplementation in young males: endocrinology, metabolic,and physiological responses at rest and during exercise - Scott C. Forbes Chapter24 - Metabolic precursors ofL-Arginine supplementation in sport: a focus on L-Citrulline and L-Ornithine - AntoniPons, Raúl Bescós, Antoni Sureda and Josep A. Tur  Section 5: Arginine and Diseasesof the Gastrointestinal Tract  Chapter25 - Arginine and its use in ameliorating Cryptosporidiumparvum infection in undernourished children - Reinaldo Barreto Oriá,Orleâncio Gomes Ripardo de Azevedo, TheídesBatista Carneiro, Aldo Ângelo Limaand Richard L. Guerrant Chapter26 - Arginine and Inflammatory Bowel Disease (IBD) - WenkaiRen, Gang Liu, Shuai Chen and Yulong Yin Chapter27 - Dietary L-arginine andintestinal recovery - IgorSukhotnik Chapter28 - Enteral and parenteral arginine supplementation in intestinal ischemia andreperfusion injury - Chun-Hong Lai and Hui-Chen Lo Chapter29 - Mucosal Protection by Arginine in the Upper Gastrointestinal Tract - KojiTakeuchi               Chapter30 - Enteral L-arginine and necrotizing enterocolitis - Sophia Zachaki,Stavroula Gavrili, Elena Polycarpou and Vasiliki I. Hatzi  Section 6: Therapeutic uses ofArginine: Diabetes, Obesity and Cardiovascular Diseases Chapter 31 - L-arginineusage in Type I diabetes: From the autoimmune event to human dietarysupplementation - Mauricio Krause, Ana PaulaTrussardi Fayh and Alvaro Reischak-Oliveira            Chapter 32- Oral l-arginine supplementation and glucose metabolism and vascular function- Lucilla D. Monti, Elena Galluccio, Barbara Fontana and Piermarco Piatti Chapter33 - Arginine enriched apples and diabetic control - AndreaEscudero, Jorge Moreno, Jesenia Acurio and Carlos Escudero Chapter34 - Beneficial impact of cod protein, arginine and otheramino acids on insulin sensitivity - VeroniqueOuellet, S. John Weisnagel, Denis R. Joanisse, Charles Lavigne, Junio Dort,André Marette and Hélène Jacques  Chapter35 - Obese subjects and supplemental L-arginine - Pawel Bogdanski, JoannaSuliburska Matylda Kr-gielska-Naröna, AnnaJablecka and Jaros-aw Walkowiak Chapter36 - Mitochondrial cardiomyopathy and usage of L-arginine - Kenichiro Arakawa,Masamichi Ikawa, Hiroshi Tada, Hidehiko Okazawaand Makoto Yoneda Chapter37 - Arginine Measurement and Concentrations in Hypertension and otherCardiovascular Disease - Cameron Naidoo and Geoffrey P. Candy Chapter38 - L-Arginine and cardiovascular disease - NorbertJ. Tripolt and Harald Sourij Chapter39 - Arginine therapy in sickle cell disease - Claudia R. Morris  Section7: Therapeutic Usesof Arginine: Cancer, Wound Healing and Infectious Disease Chapter40 - Role of arginine in surgical patients with head and neck cancer - Daniel de Luis, Rocio Aller and Pablo Casas-Rodera Chapter41 - Arginine-Incorporated Albumin Mesospheres: A Drug Delivery System forCancer Therapy - Hung-Yen Lee, Kamal A. Mohammed and Nasreen Najmunnisa                         Chapter42 - Use of L-arginine and glycine supplementation to reduce radiotherapydamage -Cristina Fajardo Diestel, Nara LimeiraHorst, Alessandra da Rocha Pinheiro Mulder and Ruy Garcia Marques Chapter43 - Arginine in Cancer Therapy - Lynn G. Feun, Medhi Wangpaichitr, Chunjing Wu,Ying-Ying Li, Min You, Macus Tien Kuo, Niramol Savaraj Chapter44 - Mechanisms of Arginine-Auxotrophic Response and Their Cancer TherapeuticImplications - Wen-Bin Tsai, Yan Long, Niramol Savaraj, Lynn G. Feun and MacusTien Kuo  Chapter45 - The role of arginine in wound healing - Alan N. Gould and Geoffrey P.Candy Chapter46 - L-arginine and bacterial translocation: implications for health - MirelleLomar Viana, Simone de Vasconcelos Generoso, Rosana das Graças Carvalho dosSantos, Valbert Nascimento Cardoso and Maria Isabel Toulson Davisson Correia Chapter47 - L-arginine in Pulmonary Tuberculosis - Anna P. Ralph 
Chapter48 - Arginine in Health and Disease: Recommended Resourcesand Further Reading - Rajkumar Rajendram, Vinood B.Patel and Victor R. Preedy