Membranes and Viruses in Immunopathology

Membranes and Viruses in Immunopathology covers the proceedings of the 1972 symposium by the same title, held at the University of Minnesota Medical School, sponsored by the Bell Museum of Pathology. This book is composed of 40 chapters that highlight the significant advances in fundamental experiments of membrane structure chemistry. Considerable chapters explore the diagnosis and analysis of slow and oncogenic virus infections, as well as the role of immunobiologic processes in the pathogenesis, prevention, and treatment of disease. The remaining chapters contain research works on the detailed mechanisms that may contribute to cancer induction and dissemination. This book will prove useful to immunopathologists and practicing physicians.

ParticipantsPrefaceAcknowledgmentsIntroductionThe Fluid Mosaic Model of the Structure of Cell MembranesThe Molecular Organization and Function of Biological Membranes: A Possible Microscopic Picture of Ionic PermeationA Resume of the Biochemical, Ultrastructural, and Functional Characteristics of Cell Membrane GlycoproteinsThe Metabolism and Turnover of Cell MembranesA Brief Account of the Use of Immunogenetics in Studying Cell SurfacesImmunochemical Properties and Genetic Relationships of H-2 Histocompatibility AlloantigensStructure of Plant Agglutinin Receptors on Human Red Blood CellsIntra-Membrane MobilitySignificance and Properties of Tumor Specific AntigensCell Junctions and Intercellular CommunicationCell Surface Interactions in Mixed Leukocyte CulturesAn Overview of the Panel Discussion on MembranesRNA and DNA Tumor Viruses-Mechanism of Cell Transformation and Role in Human CancerEmbryonic Antigens in Virally Transformed CellsCyclic AMP and the Growth of Transformed CellsSurveillance Mechanisms and MalignancyHerpesviruses as Infectious and Oncogenic Agents in Man and Other Vertebrates"Spontaneous" Release of Type C Viruses from Clonal Lines of "Spontaneously" Transformed BALB/3T3 CellsRNA's as Templates for the Virion DNA PolymeraseImmunological Studies of Mammalian Type C Viral ProteinsGenetic Factors Involved in C-Type RNA Virus ExpressionAlterations of Complex Lipid Metabolism in Tumorigenic Virus-Transformed CellsAnimal Models of Slow Viral DiseaseNeurologic Diseases of Man with Slow Virus EtiologyProgressive Pneumonia, Maedi, and Visna as Slow Virus InfectionsDiscussion of Tumor Viruses and Slow Virus InfectionsOverview of Development, Organization, Function of Lymphoid System and Human DiseaseTraffic of Cellsand Development of ImmunityModels of Immunologie DiseasesComplement and Human DiseaseVirus Induced Autoimmune Disease: Viruses in the Production and Prevention of Autoimmune DiseaseGlomerular Capillary Permeability and Experimental Nephrotic SyndromeMechanism of Lysosomal Enzyme Release in Gout and Immunologie Tissue InjuryCytotoxic Lymphocytes, Blocking Serum Factors and "Unblocking" Antibodies in Cancer PatientsMixed Haemadsorption and Immunofluorescence Studies on Immunocompetition at the MembraneHumoral Tumor Immunity in Man: Possible Role in Host Defense Against CancerModification of Immunogenicity in Experimental Immunotherapy and ProphylaxisManipulation of the Immune Response towards Immunotherapy of CancerAn Overview of the Panel Discussion on Immunology