Monoclonal Antibodies Against Bacteria

Monoclonal Antibodies Against Bacteria, Volume III covers the basis for understanding developments of practical importance in the health sciences within the area of microbiology and infectious diseases, focusing on advances made possible by monoclonal antibodies. This 12-chapter volume specifically considers the basic principles of hybridoma technology. The introductory chapters deal with treponemal antigens of significance for understanding syphilis, yaws, pinta, salmonellosis, and other gastroenteropathies. The subsequent chapters highlight pediatric infections and the strategies for molecular analyses of bacterial antigens, focusing on cell walls, S layers, and sheaths. The remaining chapters examine the bacterial toxins involved in gaseous gangrene and other forms of cell damage, such as diphtheria, caries and periodontal diseases, and bacteria relevant to animal sciences. This book will prove useful to internists, pediatricians, surgeons, dentists, veterinarians, clinical pathologists, and laboratory technologists.

ContributorsPrefaceContents of Previous Volumes1 Identification and Characterization of Treponema pallidum Antigens by Monoclonal Antibodies I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References2 Diagnostic Uses of Monoclonal Antibodies to Salmonella I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References3 Monoclonal Antibodies and Immunodetection Methods for Vibrio cholerae and Escherichia coli Enterotoxins I. Introduction II. Background III. Results and Discussion IV. Conclusions and Prospects for the Future V. Summary References4 Monoclonal Antibodies Against Campylobacter Strains I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References5 Monoclonal Antibodies to the Lipopolysaccharide and Capsular Polysaccharide of Bacteroides fragilis I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References6 Monoclonal Antibodies Against Surface Components of Streptococcus pneumoniae I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References7 Monoclonal Antibodies to Bordetella pertussis I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References8 Molecular Structures of Bacteria Elucidated by Monoclonal Antibodies with Special Reference to Antigenic Determinants of the Methanogens' Envelopes I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References9 Monoclonal Antibodies Against Clostridium perfringens - Toxin (Perfringolysin O) I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References10 Monoclonal Antibodies Against Diphtheria Toxin: Their Use in Analysis of the Function and Structure of the Toxin and Their Application to Cell Biology I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References11 Application of Monoclonal Antibodies to the Study of Oral Bacteria and Their Virulence Factors I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Prospects for the Future VI. Summary References12 Current and Future Applications of Monoclonal Antibodies Against Bacteria in Veterinary Medicine I. Introduction II. Background III. Results and Discussion IV. Conclusions V. Summary ReferencesIndex