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Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. A substantial proportion of human genes show alternative splicing and mis-regulation of Pre-mRNA splicing is seen in several cancers.This book further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing, and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving towards revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs. Technical topics discussed in the book include: . Alternative splicing and cancer. Cancer imaging. Nanomaterials in infectious diseases. Nanomedicine in oxidative stress and cancer. Nanoparticle based drug delivery systems
Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra
Series Note Preface Acknowledgements List of Figures List of Tables 1 Alternative Splicing and Cancer2 Non-coding RNAs as Molecular Tools 3 PPAR Responsive Regulatory Modules in Breast Cancer 4 Animal Model of Cancer and Infection 5 Potential Application of Natural Compounds for the Prevention and Treatment of Hepatocellular Carcinoma 6 Nanomaterials: A Ray of Hope in Infectious Disease Treatment 7 Nanomedicine for the Treatment of Oxidative Stress Injuries8 Rational Design of Multifunctional Nanoparticles for Targeted Cancer Imaging and Therapy9 Nanomedicine for the Treatment of Breast Cancer 10 Nanoparticle-Based Drug Delivery Systems: Associated Toxicological Concerns and Solutions 11 Biodegradable Carrier Systems for Drug and Vaccine Delivery About the Editors About the Contributors Index