The Antigens

The Antigens, Volume IV is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from the immune reactions of lipids and lipid model membranes to the immunology of antibiotics and protective antigens of bacteria. Antigens of pathogenic fungi are also explored, along with adjuvants and antigenic competition. Comprised of seven chapters, this volume begins with a review of lipids as antigens, followed by a discussion on the immunological aspects of antibiotics. The next two chapters are concerned with more complex antigens, namely, bacteria and fungi, as well as the relationship between immunity and infection. The last three chapters deal with three important areas of immunology: antigenic competition, adjuvants, and lectins. In particular, the chemistry of lectins and their application to immunology are examined. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

List of ContributorsPrefaceContents of Other VolumesChapter 1 Immune Reactions of Lipids and Lipid Model Membranes I. Introduction II. Nonliposomal Lipid Model Membranes III. Liposomal Model Membranes IV. Glycolipids V. Phospholipids VI. Glycophospholipids VII. Cell-Mediated Immunity VIII. Miscellaneous IX. Concluding Remarks ReferencesChapter 2 Immunology of the Antibiotics I. Introduction II. Clinical and Experimental Immunology III. Experimental Procedures and Techniques ReferencesChapter 3 Protective Antigens of Bacteria I. Protective Antigens of Bacteria II. Humoral and Cellular Mechanisms of Immunity to Bacterial Infections III. Antibacterial Mechanisms at Secretory Surfaces IV. Problems of Assessing Protection by Vaccines V. Protective Antigens of Streptococci VI. M Proteins VII. Use of M Proteins as Vaccines VIII. Protective Antigens of Neisseria meningitidis IX. Protective Antigens of Neisseria gonorrhoeae X. Protective Antigens of Shigellae XI. Protective Antigens of V. cholerae XII. Conclusions ReferencesChapter 4 Antigens of Pathogenic Fungi I. Introduction II. Aspergillosis III. Candidiasis IV. Coccidioidomycosis V. Cryptococcosis VI. The Dermatophytoses VII. Histoplasmosis VIII. North American Blastomycosis IX. Sporotrichosis ReferencesChapter 5 Antigenic Competition I. Introduction II. Experimental Systems of Antigenic Competition III. Mechanisms of Antigenic Competition IV. Addendum ReferencesChapter 6 Adjuvants I. Introduction II. Inorganic Compounds III. Mineral Oil and Oil-Water Emulsions IV. Bacteria and Their Components V. Nucleic Acids and Polynucleotides VI. Miscellaneous Substances VII. Concluding Remarks ReferencesChapter 7 Lectins: Their Chemistry and Application to Immunology I. Introduction II. History (1888-1963) III. Purification and Molecular Properties of Lectins IV. Interaction of Lectins with Cells V. Cell Separation with Lectins VI. Isolation of Lectin Receptors VII. Interaction with Soluble Glycoproteins VIII. Lectins as Antigens IX. Role in Nature ReferencesAuthor IndexSubject Index