Algal and Fungal Toxins

Microbial Toxins, Volume VII: Algal and Fungal Toxins reviews research and investigations on algal and fungal toxins. This book discusses the distribution of poisonous dinoflagellates; pharmacology of blue-green algal toxins; control of Prymnesium and detection of toxin in nature; and F-2 (zearalenone) estrogenic mycotoxin from Fusarium. The effect of Fusarium toxins in animals; mycotoxins produced by Fusarium tricinctum NRRL 3249; and mold growth and production and isolation of trichothecenes are also elaborated. This publication likewise covers the chemistry of scirpene toxic substances of Fusarium nivale; isolation of salivation factor; and mammalian toxicity of epidithiadioxopiperazines. This volume is a useful reference for scientists and graduate students in various disciplines -microbiology, biochemistry, pharmacology, epidemiology, oncology, and related fields.

List of ContributorsPrefaceContents of other VolumesSection A Algal Toxins 1. The Dinoflagellate Poisons I. Introduction II. Distribution of Poisonous Dinoflagellates III. Paralytic Shellfish Poison and Its Source in the Dinoflagellates IV. Other Types of Poisons from Dinoflagellates V. Culturing of Dinoflagellates as a Source of Poison VI. Physiological Action of Shellfish and Dinoflagellate Poisons References 2. Blue-Green and Green Algal Toxins I. Introduction II. Isolation and Culture III. Toxic Blue-Green Algae IV. Toxic Freshwater Dinoflagellate V. Pharmacology of Blue-Green Algal Toxins VI. Ecological Problems of Algal Blooms VII. Conclusion References 3. Toxins of Chrysophyceae I. Introduction II. Chemical and Physical Properties of Prymnesium Toxin III. Biological Activities of Prymnesium Toxin IV. Biosynthesis of Prymnesium Toxin V. Control of Prymnesium and Detection of Toxin in Nature VI. Other Toxic Chrysophyceae ReferencesSection B Fungal Toxins, Toxins of Fusarium 4. F-2 (Zearalenone) Estrogenic Mycotoxin from Fusarium I. Introduction II. Chemical Properties and Synthesis III. Biosynthesis and Biochemistry IV. Biological Activity References 5. Alimentary Toxic Aleukia I. History II. Epidemiology III. Etiology IV. Effect of Fusarium Toxins in Animals V. Clinical Characteristics of Alimentary Toxic Aleukia VI. Pathological Findings VII. Prophylaxis and Treatment References 6. Toxin-Producing Fungi from Fescue Pasture I. Introduction II. Mycotoxins and Fescue Foot III. Mycotoxins Produced by Fusarium tricinctum NRRL 3249 IV. Fusarium Toxins and Fescue Toxicity References 7. 12,13-Epoxytrichothecenes I. General Description II. Discovery III. Mold Growth and Production and Isolation of Trichothecenes IV. Chemistry V. Biological Activity VI. Assay of Trichothecenes VII. Metabolism and Biosynthesis VIII. Discussion References 8. Toxins of Fusarium Nivale I. Introduction II. Chemistry of Scirpene Toxic Substances of Fusarium Nivale III. Biological Effects ReferencesSection C 9. Rhizoctonia Toxin I. Introduction II. Isolation of Salivation Factor III. Chemistry of Slaframine IV. Biosynthesis of Slaframine V. Physiological Studies VI. Summary ReferencesSection D 10. The Toxicology of Sporidesmins and Other Epipolythiadioxopiperazines I. Introduction II. Production of Epipolythiadioxopiperazines III. Chemistry of Epipolythiadioxopiperazines IV. Toxicity of Epidithiadioxopiperazines V. Mammalian Toxicity of Epidithiadioxopiperazines ReferencesAuthor IndexSubject Index