Management of Hemostasis and Coagulopathies for Surgical and Critically Ill Patients

Management of Hemostasis and Coagulopathies for Surgical and Critically Ill Patients: An Evidence-Based Approach offers a concise guide to a sub-specialty of transfusion medicine from the clinical laboratory perspective. It focuses on the clinical tests that may be done during preoperative assessment, intraoperative, and postoperative assessment and management of surgical or critically ill patients. Management of hemostasis and coagulopathies is approached from an evidence-based perspective-the coagulation status of a patient according to the laboratory test results. Algorithms and decision-support software, designed by the authors, guide clinicians with an additional tool to base transfusion dosage on specific laboratory results, including the use of an artificial neural network for predicting more accurate blood use. Chapters reflect the experience of all three authors who have successfully applied the algorithm for better patient management as well as decreased wastage of expensive blood products, from both the clinical laboratory/pathology and clinical medicine perspective. This book will appeal to a broad section of clinical laboratory and medical practitioners from hematopathology, to internal medicine, surgery, and anesthesiology. For hematopathologists and pathologists who are involved in laboratory medicine and transfusion medicine, this book will help them understand the proper utilization of blood products and how to avoid unnecessary waste and costs for the hospital. For general surgery practitioners, this book will provide practical guidelines on how to use blood products rationally for best medical practice. Internists will also gain insight from this book, learning which patients are at higher risk of bleeding during surgery so that they can alert their clinical colleagues.

Andy Nguyen received his BS and MS degrees in Mechanical Engineering from the University of Houston. He had been working as a mechanical engineer for 5 years prior to enrolling in medical school. He obtained his MD degree from the University of Texas Medical Branch-Galveston and received his pathology residency training from the Pathology and Laboratory Medicine Department of the University of Texas Health Sciences Center located at the Texas Medical Center at Houston. After completing his residency, he stayed on as a faculty member and is currently a Full Professor of Pathology and Laboratory Medicine. He has clinical and research interests in hematopathology, coagulopathy, and pathology informatics. Dr. Nguyen has published numerous scientific papers, written many invited review articles, and contributed to several textbooks. He has also received multiple teaching awards from the Pathology Department and from the Office of the Dean.

1. Coagulation based tests and their interpretation2. Blood bank testing and blood products3. Pharmacotherapy with Antiplatelet, Anticoagulant and their Reversing Agents4. Antiplatelets and anticoagulants5. Pre-operative assessment of patients6. Intraoperative and Postoperative Assessment and Management of Coagulopathy7. Specific clinical situations8. Decision-Support Software for Coagulopathy