Applications of Large Language Models (LLM) in Healthcare Systems

This book offers a comprehensive exploration into the role of Large Language Models (LLMs) in modern healthcare. It focuses specifically on the lifecycle of LLM deployment in healthcare settings, including transparency, accountability, data privacy, and regulatory compliance to ensure safe and effective use.

Azadeh Zamanifar is currently head of computer engineering department at Islamic Azad university, science and research branch. She received her B.Sc. degree in Computer Engineering (Hardware) from Tehran University in 2002. She went on to complete her M.Sc. degree in Computer Engineering (Software) at the University of Science and Technology in 2008, before obtaining her Ph.D. in Software Engineering from Shahid Beheshti University in Tehran, Iran. Currently, she serves as the Head of the Software and AI Department at Islamic Azad University Science and Research Branch. Her research interests include health care systems, Machine Learning and distributed systems. Miad Faezipour is an associate professor of electrical and computer engineering technology at the School of Engineering Technology, Purdue University. She is also a full member of the Regenstrief Center for Healthcare Engineering (RCHE) and a core faculty member of the Applied AI Research Center (AARC) at Purdue University. She is the founder and director of the Digital/Biomedical Embedded Systems and Technology (D-BEST) research laboratory. She received the M.Sc. and Ph.D. degrees in electrical engineering from the University of Texas at Dallas. Prior to joining Purdue University in August 2021, she has served the Computer Science & Engineering and Biomedical Engineering programs of the University of Bridgeport, CT as a faculty member for ten years. Her research interests primarily include healthcare technology, digital/biomedical embedded hardware/software co-designs, biomedical signal/image processing, computer vision, healthcare/biomedical informatics, artificial intelligence and AI-based bio-data augmentation. She is a Senior Member of IEEE, EMBS and the IEEE Women in Engineering. Farhad Soleimanian Gharehchopogh: Department of computer engineering, Urmia branch, Islamic Azad university, Urmia, Iran, Farhad Soleimanian Gharehchopogh an Associate Professor in the Department of Computer Engineering at Urmia Branch, Islamic Azad University, since 2015, brings a wealth of experience to his role. He received a B.S. from the Shabestar Branch, Islamic Azad University in 2002, and an M.S. from Cukurova University in Adana, Turkey. He earned his Ph.D. in Computer Engineering from Hacettepe University in 2015. Dr Farhad has published over 200 journal articles, many in high-impact journals, with over 9000 citations. His research interests span Data Mining and Machine Learning. Much of his work has been on improving the understanding, design, and performance of algorithms, mainly through the application of engineering. Amirfarhad Farhadi holds a Ph.D. in Artificial Intelligence and is currently a Postdoctoral Fellow at Iran University of Science and Technology. He also serves as an Adjunct Professor in the Department of Computer Engineering at the Science and Research Branch of Islamic Azad University. His research expertise spans Artificial Intelligence (AI), machine learning, deep learning, transfer learning, reinforcement learning, natural language processing (NLP), and healthcare systems. Dr. Farhadi serves as a reviewer for esteemed journals, including IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI) and IEEE Transactions on Neural Networks and Learning Systems, among others. In addition to his academic contributions, he holds patents in robotics and actively participates in the AI industry, focusing on innovative applications and technological advancements.

Preface List of Contributors Editor Bios Chapter 01 Large Language Models in Clinical Application Homayoun Safarpour, Amirfarhad Farhadi, Martin Cunneen, György Molnár, Enik- Nagy Chapter 02 Administrative Efficiency: Providing Healthcare Operations Alireza Taheri, Amirfarhad Farhadi, Azadeh Zamanifar, Amirmohammad Mataji Chapter 03 LLMs in drug discovery, clinical trial analysis, and medical literature review Sina Abbaskhani, Deniz NoorMohammadzadehMaleki, Amirfarhad Farhadi, and Azadeh Zamanifar Chapter 04 LLMs For Personalaized Medicine and Treatment planning Amirfarhad Farhadi, and Nasser Mozayeni Chapter 05 for Public Health Surveillance and Outbreak Arezou Naghib, Farhad Soleimanian Gharehchopogh, and Parisa Tavana Chapter 06 The Role of Large Language Models in Delivering Artificial Intelligence-Based Psychological Interventions and Therapies Arezou Naghib, Farhad Soleimanian Gharehchopogh, and Azadeh Zamanifar Chapter 07 Explainable AI (XAI): Making LLM Decisions Transparent and Trustworthy Amirfarhad Farhadi, Azadeh Zamanifar, Fouad Bahrpeyma Chapter 08 Ethical Implications for LLMs Mohammad Saleh, and Azadeh Tabatabaei Chapter 09 Limitations of Large Language Models in Healthcare Systems Farshid Babapour Mofrad , and Midya Yousefzamani Chapter 10 Future Trends and Innovations in Healthcare Systems Using LLMs Kiana Pilevar Abrisham, and Khalil Alipour