Herpes Simplex Varicella and Zoster

Herpes Simplex Varicella and Zoster: Clinical Manifestations and Treatment provides an authoritative and updated clinical observation on two viruses-herpes simplex varicella and zoster. This book focuses on the similarities in tissue tropisms and character of the lesions of the two viruses. This text not only outlines the various disease patterns but gives guidance to rational treatment with antiviral agents. The topics covered include the historical background of the two viruses; description and clinical manifestations of infection in man of herpes simplex (HSV) and varicella-zoster (V-Z); definition of B virus (herpesvirus simiae); recurrent infection zoster; and treatment. This publication is intended for clinicians, but can also be a good reference for medical students and individuals conducting research in the field of virology, specifically on venereal diseases.

Preface Introduction 1. Historical Background 2. Herpes Simplex The Virus Aetiology Morphology and Replication Herpes Antigenic Types Pathology and Pathogenesis HSV and Carcinoma Laboratory Diagnosis Serology Immunity and Recovery 3 Clinical Manifestations of HSV Infection The Primary Infection Epidemiology Primary Infection of the Mouth and Lips Ocular Infection with HSV Primary Lesions of the Skin Herpetic Whitlows Traumatic Herpes Eczema Herpeticum. Juliusberg's Pustulosis Acuta Varioliformis. Kaposi's Varicelliform Eruption Generalized Primary Infections Hepatitis due to HSV HSV Meningitis HSV Encephalitis The Recurrent Infection Complications in Recurrent HSV Infections Herpesvirus Infection in Burned Patients Recurrent Herpes Simplex and Erythema Multiforme Genital Herpes Simplex Infections Differential Diagnosis 4. B Virus Infection Aetiology The Virus Pathology Laboratory Diagnosis Antigenic Relationship with HSV 5. Varicella-Zoster The Virus Aetiology Morphology and Replication Pathology and Pathogenesis Laboratory Diagnosis Serology Immunity and Recovery 6. Clinical Manifestations of V-Z Virus Infection Chickenpox. Varicella Epidemiology and Infectivity Clinical Manifestations Differential Diagnosis from Smallpox Complications Varicella pneumonias Encephalitis Purpura Fulminans. Haemorrhagic Chickenpox Congenital and Neonatal Varicella7. The Recurrent Infection Zoster. Shingles Epidemiology Provocation of Zoster The Usual Clinical Picture in Zoster Pain in Zoster Dissemination of Virus in Zoster The Segmental Distribution of Zoster and some Complications Recurrent Zoster Ophthalmic Zoster Motor Zoster Zoster Encephalomyelitis 8 Treatment Some Problems in Antiviral Chemotherapy Halogenated Deoxyuridines Idoxuridine; 5-iodo-2'-deoxyuridine; IUdR; IDU D-Arabinofuranosyl Nucleotides 1-ß-D arabinofuranosylcytosine (cytarabine; cytosine arabinoside; CA; Ara-C) 9-ß-D arabinofuranosyladenine (vidarabine; adenosine arabinoside; adenine arabinoside; Ara-A) Treatment of HSV Infection Cold Sores HSV Gingivostomatitis Severe HSV Stomatitis Ocular HSV Lesions Herpetic Whitlows Erythema Multiforme provoked by Recurrent HSV Lesions Eczema Herpeticum Generalized HSV Infection HSV Encephalitis Genital Herpes Treatment of B Virus Infection Treatment of V-Z Infection Chickenpox Uncomplicated Segmental Zoster Ophthalmic Zoster Motor Zoster Generalized Zoster Zoster Encephalitis Chickenpox, Zoster and HSV Infections during Pregnancy References Index