Biology of Parasitic Spirochaetes

Biology of Parasitic Spirochaetes presents the proceedings of the First Symposium on the Biology of the Parasitic Spirochetes. This volume and the symposium from which it arises aims to present an overview and the current information available on the parasitic spirochetes. The etiological agents of the treponematoses, leptospiroses, and the relapsing fevers are discussed by distinguished investigators who provide extensive and sometimes unique knowledge of these bacteria. In addition to providing a valuable resource of information, this volume should reveal the gaps in our knowledge and stimulate interest in some of the neglected areas of spirochetal biology. This volume contains 32 papers organized into eight sections. Section I contains papers on spirochete morphology. Section II presents studies on spirochete cultivation, composition, and physiology. Sections III and IV deal with the classification of the spirochetes and the epidemiology of the spirochetoses, respectively. Section V focuses on laboratory diagnosis of the spirochetoses. Section VI examines the pathogenesis of spirochetal diseases. Section VII takes up immunity and spirochetal diseases while Section VIII covers the treatment and control of the spirochetoses.

List of ContributorsPrefaceSection I Spirochete Morphology Chapter 1 Some Perspectives for Thinking about Spirochaetal Structure Chapter 2 Treponema and Borrelia Morphology Chapter 3 Morphology of LeptospiresSection II Spirochete Cultivation, Composition and Physiology Chapter 4 Comparative Spirochete Physiology and Cellular Composition Chapter 5 Cultivation, Composition and Physiology of Avirulent Treponemes Chapter 6 Tissue Culture and Treponema pallidum Chapter 7 Nutrition of Leptospires in Bovine Albumin Polysorbate Medium Chapter 8 Cultivation and Physiology of Relapsing Fever BorreliaeSection III Classification of the Spirochetes Chapter 9 Classification of Spirochaetes in General and of the Genus Leptospira in Particular Chapter 10 Pathogenic Treponemes Chapter 11 Classification of Non-Pathogenic Tréponèmes, Borrelia and SpirochaetaSection IV Epidemiology of the Spirochetes Chapter 12 The Epidemiology of the Spirochetoses, a Worldwide View Chapter 13 Epidemiology of Syphilis and the Non-Venereal Treponematoses Chapter 14 Epidemiologie Trends of Leptospirosis in the United States, 1965-1974 Chapter 15 The Epidemiology of the Relapsing FeversSection V Laboratory Diagnosis of the Spirochetoses Chapter 16 Laboratory Diagnosis of Treponematoses (with Emphasis on Syphilis) Chapter 17 Laboratory Diagnosis of Leptospirosis Chapter 18 The Diagnosis of Relapsing FeversSection VI Spirochetal Diseases-Pathogeneis Chapter 19 The Determinants of Microbial Pathogenicity in Relation to Spirochetal Disease Chapter 20 The Pathogenesis of Syphilis and the Related Treponematoses Chapter 21 Periodontal Disease and the Treponemes Chapter 22 Intestinal Treponematoses Chapter 23 Pathogenesis of Leptospirosis Chapter 24 Relapsing Fever-PathogenesisSection VII Immunity and Spirochetal Diseases Chapter 25 Pathological Effects of Immunologie Responses Chapter 26 The Role of Immunologie Responses in Protection against Syphilis Chapter 27 Immunity in Leptospirosis Chapter 28 Immunity in Relapsing FeverSection VIII Treatment and Control of the Spirochetoses Chapter 29 Treatment of Syphilis Chapter 30 Endemic Syphilis, Yaws and Pinta Chapter 31 Treatment and Control of Leptospirosis Chapter 32 Relapsing Fever-Treatment and ControlSubject Index