CDC Yellow Book 2026

The CDC Yellow Book has been a trusted resource among healthcare professionals for over half a century. It compiles the US government's current travel health guidance, providing travel medicine specialists, healthcare professionals, and travelers with expert guidance for safe and healthy international travel. Along with disease-specific prevention and treatment recommendations, this comprehensive reference text equips readers with the background and context needed to understand and address public health threats associated with all types of international travel. With chapters written by subject matter experts in the travel medicine field, this edition features the following topics:
Vetted recommendations for pre-travel vaccinations and preventative care, including public health guidance for specific destinations and types of travel
Profiles of the most common travel-associated infections and health conditions
Special sections tailored to travelers with additional considerations, including travelers with HIV, immunocompromised travelers, severely allergic travelers, and travelers with substance use disorders
Updated advice for family travel, including pregnant travelers, traveling safely with infants and children, and traveling with pets and service animals
Illustrated with vividly drawn destination maps conveying the endemicity of malaria, yellow fever, and other infectious diseases
Expanded section on pre- and post-arrival medical evaluations for refugees, immigrants, and other migrant populations
Expanded content on the clinical approach to international travelers returning with respiratory complaints, diarrhea, dermatologic conditions, parasitic disease, and more
Public health guidance for popular itineraries in Africa and the Middle East, the Americas and the Caribbean, and Asia

Eric Halsey, MD, is an adult infectious diseases physician who has worked in travel and tropical medicine for over 20 years. He formerly led the Virology Department at NAMRU-6 in Lima, Peru, and was the CDC case management lead for the US President's Malaria Initiative. He currently is the Chief Medical Officer of the CDC Travelers' Health Branch. Dr. Halsey remains board certified in internal medicine and infectious diseases and volunteers as an HIV and travel medicine physician in Atlanta hospitals and serves on the CDC Domestic Malaria After Hours Hotline.

Preface Acknowledgements CDC Contributors External Contributors List of Maps, by Topic
Section 1: Preparing International Travelers
Section 2: Travelers with Additional Considerations
Section 3: Environmental Hazards and Risks
Section 4: Travel-Associated Infections and Diseases
Section 5: Health Care Abroad
Section 6: Family Travel
Section 7: Travel by Air and Sea
Section 8: Travel for Work and Other Reasons
Section 9: Refugees, Immigrants, and Migrants
Section 10: Post-Travel Evaluation
Section 11: Popular Destinations Section 11, Part 1: Africa and The Middle East
Section 11, Part 2: The Americas and The Caribbean
Section 11, Part 3: Asia
Appendix