Stem Cells

Stem Cells: Scientific Facts and Fiction, Third Edition, provides a state-of-the-art overview on the field of stem cells and their current applications. The book incorporates the history and firsthand commentaries in the field from clinical and research leaders, covering interesting topics of note, including the first clinical trials to treat Parkinson disease, macular degeneration, and corneal replacement, the cloning of monkeys, the organoid field, and CRISPR-edited genomics. In addition, coverage of adult, embryonic stem cells and iPS cells is included. This new edition distinguishes itself from the multiplicity of websites about stem cells with a broad view of the field.

Christine Mummery is a Professor of Developmental Biology at Leiden University Medical Centre in the Netherlands and head of the Department of Anatomy and Embryology. Her research concerns heart development and the differentiation of pluripotent human stem cells into the cardiac and vascular lineages and using these cells as disease models, for safety pharmacology, drug discovery and future cardiac repair. Immediate interests are on developing biophysical techniques for characterization and functional analysis of cardiovascular cells from hPSC. She was recently awarded a multimillion grant for this purpose and is awardee of a prestigious European Research Council Advanced Grant. A member of the Royal Netherlands Academy of Science, and former board member of the International Society of Stem Cell research and the Netherlands Medical Research Council, she's editor in chief of the ISSCR journal Stem Cell Reports and is also on the editorial boards of Cell Stem Cell, Cardiovascular Research and Stem Cells.

1. The Biology of the Cell 2. Embryonic Development 3. What are Stem Cells? 4. Of Mice and Men: The History of Embryonic Stem Cells 5. Origins and Types of Stem Cells: What's in a Name? 6. Cloning: History and Current Applications 7. Regenerative Medicine: Clinical Applications of Stem Cells 8. Stem Cells in Veterinary Medicine 9. Cardiomyocytes from Stem Cells: What can we do with them? 10. Adult Stem Cells: Generation of Self-Organizing Mini-Organs in a Dish 11. Stem Cell Tourism 12. Cancer Stem Cells: Where do they come from and where are they going? 13. Human Stem Cells for Organ-on-Chips: Clinical Trials without Patients 14. Stem Cells for Discovery of Effective and Safe New Drugs 15. Patients, Opportunities, and Challenges: Legal and Intellectual Property Issues associated with Stem Cells 16. Stem Cell Perspectives: A Vision of the Future