Cannabis and Cannabinoids

Study the latest research findings by international experts!This comprehensive volume presents state-of-the-art scientific research on the therapeutic uses of cannabis and its derivatives. All too often, discussions of the potential medical uses of this substance are distorted by political considerations that have no place in a medical debate. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential features fair, equitable discussion of this emerging and controversial medical topic by the world's foremost researchers.Cannabis and Cannabinoids examines the benefits, drawbacks, and side effects of medical marijuana as a treatment for various conditions and diseases. This book discusses the scientific basis for marijuana's use in cases of pain, nausea, anorexia, and cachexia. It also explores its possible benefits in glaucoma, ischemia, spastic disorders, and migraine.Cannabis and Cannabinoids examines all facets of the medical use of marijuana, including: - botany - history - biochemistry - pharmacology - clinical use - toxicology - side effectsCannabis and Cannabinoids is a reference work that will become indispensable to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public. No other book available offers this comprehensive, even-handed look at a deeply divisive subject.

Franjo Grotenhermen, MD, has worked in the fields of internal medicine, surgery, and integrative medicine. Since 1994 he has been researching medical uses of hemp at the Nova Institut. He is also a member of the working group on quality of life for cancer patients at the Department of Internal Medicine at the University of Cologne. Ethan Russo, MD, is a child and adult neurologist at Montana Neurobehavioral Specialists. He has had a lifetime interest in medicinal plants. He holds a faculty position in the Department of Pharmaceutical Sciences and is also Clinical Associate Professor in the Department of Medicine at the University of Washington.

Part 1 PART I: BOTANY, TAXONOMY, CHEMISTRY, AND HISTORY; Chapter 1 Botany of Natural Cannabis Medicines, Robert C.Clarke, David PaulWatson; Chapter 2 Chapter 2 Taxonomy of Cannabinoids, David W.Pate; Chapter 3 Chapter 3 Chemical Constituents of Cannabis, Mahmoud A.ElSohly; Chapter 4 Chapter 4 History of Cannabis in Western Medicine, Manfred Fankhauser; Part 2 Part II: Pharmacology and Pharmacokinetics; Chapter 5 Chapter 5 Effects of Cannabis and the Cannabinoids, Franjo Grotenhermen; Chapter 6 Chapter 6 Pharmacokinetics, Rudolf Brenneisen; Chapter 7 Chapter 7 Sites and Mechanisms of Action, Roger G.Pertwee; Chapter 8 Chapter 8 Mechanisms of Cannabinoid Analgesia, Chris W.Vaughan, MacDonald J.Christie; Chapter 9 Chapter 9 Cannabinoids As Neuroprotectants Against Ischemia, Aidan Hampson; Chapter 10 Chapter 10 Possible Mechanisms in Autoimmune Diseases, RobertMelamede; Part 3 PART III: INDICATIONS FOR CANNABIS AND THC; Chapter 11 Chapter 11 Review of Therapeutic Effects, FranjoGrotenhermen; Chapter 12 Chapter 12 Medical Use of Cannabis: Experience in California, Dale Gieringer; Chapter 13 Chapter 13 Anorexia and Cachexia, Martin Schnelle, Florian Strasser; Chapter 14 Chapter 14 Antiemetic Effects of Cannabinoids, Terry Plasse; Chapter 15 Chapter 15 Pain Therapy, Anita Holdcroft; Chapter 16 Chapter 16 Migraine, EthanRusso; Chapter 17 Spastic Disorders, Richard E. Musty, Paul Consroe; Chapter 18 Chapter 18 Movement Disorders, Kirsten R.Müller-Vahl, HansKolbe, UdoSchneider, Hinderk M.Emrich; Chapter 19 Chapter 19 Glaucoma and Cannabinoids, David W. Pate; Chapter 20 Chapter 20 Dependency and Cannabis, Tod H.Mikuriya; Part 4 PART IV: RISKS AND SIDE EFFECTS; Chapter 21 Chapter 21 Review of Unwanted Actions of Cannabis and THC, FranjoGrotenhermen; Chapter 22 Chapter 22 Acute Effects of Cannabis and the Cannabinoids, F. MarkusLeweke; Chapter 23 Chapter 23 Cannabis and Dependence, WendySwift, WayneHall; Chapter 24 Chapter 24 Pregnancy, Peter A.Fried; Chapter 25 Chapter 25 Immune System, Guy A. Cabral; Chapter 26 Chapter 26 Hormonal System and Reproduction, Laura L.Murphy; Chapter 27 Chapter 27 Long-Term Effects of Cannabis on Psyche and Cognition, NadiaSolowij, Brin F. S.Grenyer; Chapter 28 Chapter 28 Cannabis and Alcohol in Motor Vehicle Accidents, Gregory B. Chesher, Marie Longo; Chapter 29 Chapter 29 Respiratory Risks from Marijuana Smoking, Donald P.Tashkin; Chapter 30 Chapter 30 Contaminants and Adulterants in Herbal Cannabis, John M.McPartland; Chapter 31 Chapter 31 Practical Hints, FranjoGrotenhermen; Part 5 PART V: OTHER CANNABINOIDS; Chapter 32 Chapter 32 Overview of Cannabinoids Under Investigation, Franjo Grotenhermen; Chapter 33 Chapter 33 Cannabidiol: Possible Therapeutic Application, Antonio W. Zuardi, Francisco S. Guimar ães, Viviane M. C. Guimar ães, Elaine A. Del Bel; Chapter 34 Chapter 34 Anandamides: Potential Glaucoma Medicine?, David W. Pate; Chapter 35 Chapter 35 Therapeutic Potential of Ajulemic Acid (CT3), Sumner H. Burstein; Chapter 36 Chapter 36 HU-211: A Cannabinoid Neuroprotective Agent, Raphael Mechoulam, Ester Shohami; Part 6 PART VI: OTHER CONSTITUENTS OF CANNABIS; Chapter 37 Chapter 37 Noncannabinoid Components, John M.McPartland, VitoMediavilla; Chapter 38 Chapter 38 Hemp Seed and Hemp Oil, Gero Leson, Petra Pless; Resources; Index;