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Inhaled Particles VI contains the proceedings of an international symposium and workshop on lung dosimetry, organized by the British Occupational Hygiene Society in cooperation with the Commission of the European Communities and held at Cambridge on September 2-6, 1985. The symposium presents results of research on the entry, destiny, and effects of respired particles, with emphasis on mechanisms and dose-response relationships. This book contains, in three separate parts, 84 papers from the symposium, 34 workshop papers, and 20 poster presentations. Parts 1 and 2 are further divided into sections. Section 1 presents several papers concerning the influence of breathing pattern and activity on regional deposition of inhaled particles. Section 2 shows comparative studies of aerosol deposition in experimental animals and humans. Subsequent sections explore the mineral content of lungs to differing exposures; biological effects of dusts; hazard parameters; dust measurement; exposure of workers to vermiculite and attapulgite; effects of dust exposure in the coal mining industry; and effects of silica dust exposure. Other topics of significance include toxicity of artificial mineral fibers and utility of magnetopneumography as a non-invasive investigational test.
PrefacePart 1: Inhaled Particles Symposium Section 1: Particle Inhalation and Deposition Influence of Breathing Mode and Activity Level on the Regional Deposition of Inhaled Particles and Implications for Regulatory Standards Tracheobronchial Deposition Predictions for Infants, Children and Adolescents Effects of Airway Branching Patterns on Particle Deposition in the Lungs Validation of an In Vivo Aerosol Probe Technique by Measurements of Deposition and Morphometry in Excised Human Lungs Deposition of Monodisperse Insoluble Aerosol Particles in the 0.005 to 0.2 µm Size Range within the Human Respiratory Tract Section 2: Deposition, Clearance and Retention Regional Deposition of Inhaled Monodisperse Coarse and Fine Aerosol Particles in Small Laboratory Animals Monte Carlo Model for Aerosol Deposition in Human Lungs Particle Deposition in Volumetric Regions of the Human Respiratory Tract Modeling an Aerosol Dispersion Test for Detecting Early Airway Changes Deposition of 0.