50 Studies Every Vascular Surgeon Should Know

50 Studies every Vascular Surgeon Should Know presents key studies that have shaped the practice of Vascular Surgery. Selected using a rigorous methodology, the studies cover topics including carotid artery disease, aortic aneurysm, peripheral artery disease, trauma, venous disease and vascular access. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implication for practice. An illustrative clinical case concludes each review to highlight the impact of the study on clinical practice. This book is a must read for vascular surgeons, especially those in training and preparing for board exams, as well as anyone who wants to learn more about the data behind clinical practice.

Julien Al Shakarchi is Consultant Vascular Surgeon, Department of Vascular Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester, UK.

Section 1: Secondary Prevention in Peripheral Arterial DiseaseJulien Al Shakarchi and Andrew Garnham1. Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE): A Randomized, Blinded Trial 2. Rivaroxaban With or Without Aspirin in Patients with Stable Peripheral or Carotid Artery Disease: Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS), an International, Randomized, Double-Blind, Placebo-Controlled Trial3. Rivaroxaban in Peripheral Artery Disease After Revascularization (VOYAGER)4. UK Medical Research Council/British Heart Foundation Heart Protection Study of Cholesterol Lowering with Simvastatin in 20,536 High-Risk Individuals: A Randomized Placebo-Controlled Trial5. Systematic Review of the Efficacy of Cilostazol, Naftidrofuryl Oxalate, and Pentoxifylline for the Treatment of Intermittent Claudication
Section 2: Cerebrovascular DiseaseJulien Al Shakarchi and Alok Tiwari6. Analysis of Pooled Data from the Randomized Controlled Trials of Endarterectomy for Symptomatic Carotid Stenosis7. Early Endarterectomy Carries a Lower Procedural Risk Than Early Stenting in Patients with Symptomatic Stenosis of the Internal Carotid Artery8. Prevention of Disabling and Fatal Strokes by Successful Carotid Endarterectomy in Patients Without Recent Neurologic Symptoms: First Asymptomatic Carotid Surgery Trial (ACST-1), a Randomized Controlled Trial9. Safety of Stenting and Endarterectomy for Asymptomatic Carotid Artery Stenosis: A Meta-analysis of Randomized Controlled Trials10. Second Asymptomatic Carotid Surgery Trial (ACST-2): A Randomized Comparison of Carotid Artery Stenting Versus Carotid Endarterectomy11. General Anesthesia Versus Local Anesthesia for Carotid Surgery (GALA): A Multicenter, Randomized Controlled Trial12. Prospective Randomized Trial of Carotid Endarterectomy with Primary Closure and Patch Angioplasty with Saphenous Vein, Jugular Vein, and Polytetrafluoroethylene: Long-Term Follow-up
Section 3: Thoracic OutletJulien Al Shakarchi and Andrew Garnham13. A Decade of Excellent Outcomes After Surgical Intervention in 538 Patients with Thoracic Outlet Syndrome14. A Systematic Review and Meta-Analysis for the Management of Paget-Schroetter Syndrome
Section 4: Thoracic Aortic DiseaseJulien Al Shakarchi and Donald Adam15. Randomized Comparison of Strategies for Type B Aortic Dissection: The Investigation of Stent Grafts in Aortic Dissection (INSTEAD) Trial16. Outcomes of 3,309 Thoracoabdominal Aortic Aneurysm Repairs17. Long-Term Results of Endovascular Repair for Descending Thoracic Aortic Aneurysms
Section 5: Abdominal Aortic DiseaseJulien Al Shakarchi18. Multicenter Aneurysm Screening Study (MASS): Cost-Effectiveness Analysis of Screening for Abdominal Aortic Aneurysms Based on 4-Year Results from a Randomized Controlled Trial19. Long-Term Outcomes of Immediate Repair Compared with Surveillance of Small Abdominal Aortic Aneurysms: United Kingdom Small Aneurysm Trial (UKSAT)20. Endovascular Repair Compared with Surveillance for Patients with Small Abdominal Aortic Aneurysms: Positive Impact of Endovascular Options for Treating Aneurysms Early (PIVOTAL) Trial21. Endovascular Versus Open Repair of Abdominal Aortic Aneurysm in 15 Years' Follow-up of the UK Endovascular Aneurysm Repair Trial 1 (EVAR 1): A Randomized Controlled Trial22. Endovascular Repair of Abdominal Aortic Aneurysm in Patients Physically Ineligible for Open Repair (EVAR 2)23. Open Versus Endovascular Repair of Abdominal Aortic Aneurysm (OVER)24. Endovascular or Open Repair Strategy for Ruptured Abdominal Aortic Aneurysm: 30-Day Outcomes from the Immediate Management of Patients with Rupture: Open Versus Endovascular Repair (IMPROVE) Randomized Trial25. Meta-analysis of Fenestrated Endovascular Aneurysm Repair Versus Open Surgical Repair of Juxtarenal Abdominal Aortic Aneurysms
Section 6: Visceral and Renal Arterial DiseaseJulien Al Shakarchi and Richard Downing26. Stenting and Medical Therapy for Atherosclerotic Renal Artery Stenosis: The Cardiovascular Outcomes in Renal Atherosclerotic Lesion (CORAL) Trial27. Patient Survival After Open and Endovascular Mesenteric Revascularization for Chronic Mesenteric Ischemia28. Splenic Artery Aneurysms: Two Decades of Experience at the Mayo Clinic29. Renal Artery Aneurysms: A 35-Year Clinical Experience with 252 Aneurysms in 168 Patients30. Open and Laparoscopic Treatment of Median Arcuate Ligament Syndrome
Section 7: Peripheral Arterial DiseaseJulien Al Shakarchi and Lewis Meecham 31. Supervised Exercise Versus Primary Stenting for Claudication Resulting from Aortoiliac Peripheral Artery Disease: The Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) Study32. Absence of Long-Term Benefit of Revascularization in Patients with Intermittent Claudication: The Invasive Revascularization or Not in Intermittent Claudication (IRONIC) Study33. Autologous Saphenous Vein and Expanded Polytetrafluoroethylene Grafts in Infra-inguinal Arterial Reconstructions: A 6-Year Prospective Multicenter Randomized Comparison34. Bypass Versus Angioplasty in Severe Ischemia of the Leg (BASIL): A Multicenter, Randomized Controlled Trial35. Is Duplex Surveillance of Value After Leg Vein Bypass Grafting? Principal Results of the Vein Graft Surveillance Randomized Trial (VGST)36. Dutch Iliac Stent Trial: Long-Term Results in Patients Randomized for Primary or Selective Stent Placement37. Risk of Death Following Application of Paclitaxel-Coated Balloons and Stents in the Femoropopliteal Artery of the Leg: A Systematic Review and Meta-analysis of Randomized Controlled Trials38. Meta-analysis of Open and Endovascular Repair of Popliteal Artery Aneurysms39. A Prospective Study of Risk Factors for Diabetic Foot Ulcer
Section 8: Venous DiseaseJulien Al Shakarchi and Isaac Nyamekye40. Long-Term Outcome After Additional Catheter-Directed Thrombolysis Versus Standard Treatment for Acute Iliofemoral Deep Vein Thrombosis (the CaVenT Study): A Randomized Controlled Trial41. Pharmacomechanical Catheter-Directed Thrombolysis for Deep Vein Thrombosis: The Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTRACT) Trial42. Long-Term Results of Compression Therapy Alone Versus Compression Plus Surgery in Chronic Venous Ulceration: The Effect of Surgery and Compression on Healing and Recurrence (ESCHAR) Study, a Randomized Controlled Trial43. A Randomized Trial of Early Endovenous Ablation in Venous Ulceration: The Early Venous Reflux Ablation (EVRA) Trial44. 5-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins: The Comparison of Laser, Surgery, and Foam Sclerotherapy (CLASS) Trial45. Comparison of Endovenous Ablation Techniques, Foam Sclerotherapy, and Surgical Stripping for Great Saphenous Varicose Veins: Extended 5-Year Follow-up of a Randomized Controlled Trial46. 2-Year Results of a Multicenter Randomized Controlled Trial Comparing Mechanochemical Endovenous Ablation to Radiofrequency Ablation in the Treatment of Primary Great Saphenous Vein Incompetence: The MARADONA Trial
Section 9: Vascular AccessJulien Al Shakarchi and Nicholas Inston47. Multiple Preoperative and Intraoperative Factors Predict Early Fistula Thrombosis: The Hemodialysis Fistula Maturation (HFM) Study48. Long-Term Functional Patency and Cost-Effectiveness of Arteriovenous Fistula Creation Under Regional Anesthesia: A Randomized Controlled Trial
Section 10: TraumaJulien Al Shakarchi and Jack Fairhead49. Durability of Endovascular Repair in Blunt Traumatic Thoracic Aortic Injury: Long-Term Outcome from Four Tertiary Referral Centers50. A Multicenter Trial of Vena Cava Filters in Severely Injured Patients