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Measles Virus and Its Biology deals with the biological and clinical problems of the viral disease, measles. This book also describes the behavior of the measles virus in terms of its immunological, biochemical, or molecular-biological aspects. The authors review the epidemiology and pathogenesis of measles and discuss how the virus flourishes and mobilizes in the human body through a close association with leukocytes and lymphoid organs. Biological characters and genetic markers of the virus can serve to separate different isolates of the measles virus from one another. Radioactive labeling techniques have detected six structural proteins associated with the virus; a schematic diagram in the book shows the structural components and the biochemical dissection of the virus. The authors also discuss that the various immune responses to the virus can be due to "variation in the patient" rather than virus mutation. The authors do not discount that the physiological behavior of the virus such as its location, number, or replication can also affect the host. This text is suitable for the clinical research workers dealing with immunology, infectious diseases, cellular chemistry, or molecular biology.
Preface1. The Biology of Measles2. The Isolation and Adaptation of Measles Virus3. Biological Characters and Genetic Markers4. Structure and Components of Measles Virus5. Non-Vegetative Functions of Measles Virus, Hemagglutination Hemolysis and Cell Fusion6. The Growth Cycle of Measles Virus7. Persistent Infection by Measles Virus8. Neuropathogenicity of Measles Virus9. Measles Virus and Subcute Sclerosing Panencephalitis-SSPE Viruses10. Immunology of Measles Virus-Epidemiology; Specific Antibodies11. Immunology of Measles Virus-Cell-Mediated Immunity12. Immunology of Measles Virus-Multiple Sclerosis and Auto Immune Diseases13. Immunology of Measles Virus-Immunization; Immunodeficient StatesReferencesSubject Index
