Mechanical Circulatory and Respiratory Support

Mechanical Circulatory and Respiratory Support, Second Edition, continues to provide a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. This new edition provides an update on the field while also introducing new elements within the field such as ex-vivo perfusion, devices for HFpEF, design for manufacture, oxygenator design, and more content on route to market. Chapters from over 60 internationally-renowned experts focuses on the entire life-cycle of mechanical circulatory and respiratory support - from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future. This second edition is a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development.

Section 1 - Before the Device 1. The Descent into Heart and Lung Failure 2. Heart and Lung Transplantation 3. Ex-vivo Organ Support Section 2 - MCRS Devices 4. Ventricular Assist Devices: Volume Displacement Pumps 5. Ventricular Assist Devices: Rotary Blood Pumps 6. Total Artificial Hearts 7. Devices for HFpEF 8. Extracorporeal Membrane Oxygenation Section 3 - Implantation and Medical Management 9. Optimising the Patient and Timing the Introduction of MCS 10. Surgical Implantation 11. Complications and Adverse Events 12. Medical Management of the Supported Patient 13. Pediatric devices Section 4 - Device Design 14. Hydraulic Design 15. Motor design and Impeller Suspension 16. Design for Manufacture 17. Pulsatile vs Continuous Flow 18. Cannula Design 19. Oxygenator Design Section 5 - Device/Patient Interaction 20. Blood-Device Interaction 21. Physiological Control 22. Systems for Power and Data Transfer 23. Wearable Systems Section 6 - Route to Market 24. Route to Market 25. Preclinical Evaluation 26. Clinical trials 27. Cost Effectiveness 28. Regulatory approvals Section 7 - Future 29. The Past, Present and Future