Mechanical Circulatory and Respiratory Support

Mechanical Circulatory and Respiratory Support, Second Edition, continues to provide a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. This new edition provides an update on the field while also introducing new elements within the field such as ex-vivo perfusion, devices for HFpEF, design for manufacture, oxygenator design, and more content on route to market.Chapters from over 60 internationally-renowned experts focuses on the entire life-cycle of mechanical circulatory and respiratory support - from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future.This second edition is a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development.
- Presents an engineering pathway to develop the most advanced medical devices- Features a clinical summary of how to select the right patients and treat them optimally while supported with these devices- Includes a detailed path to market for those developing new devices in this field

Section 1 - Before the Device1. The Descent into Heart and Lung Failure2. Heart and Lung Transplantation3. Ex-vivo Organ SupportSection 2 - MCRS Devices4. Ventricular Assist Devices: Volume Displacement Pumps5. Ventricular Assist Devices: Rotary Blood Pumps6. Total Artificial Hearts7. Devices for HFpEF8. Extracorporeal Membrane OxygenationSection 3 - Implantation and Medical Management9. Optimising the Patient and Timing the Introduction of MCS10. Surgical Implantation11. Complications and Adverse Events12. Medical Management of the Supported Patient13. Pediatric devicesSection 4 - Device Design14. Hydraulic Design15. Motor design and Impeller Suspension16. Design for Manufacture17. Pulsatile vs Continuous Flow18. Cannula Design19. Oxygenator DesignSection 5 - Device/Patient Interaction20. Blood-Device Interaction21. Physiological Control22. Systems for Power and Data Transfer23. Wearable SystemsSection 6 - Route to Market24. Route to Market25. Preclinical Evaluation26. Clinical trials27. Cost Effectiveness28. Regulatory approvalsSection 7 - Future29. The Past, Present and Future