Principles of Tissue Engineering

Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production - is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.

PART I - Foundations Chapter 1 - Introduction Bedir Tekinerdogan, Dominique Blouin, Hans Vangheluwe, Miguel Goulão, Paulo Carreira, Vasco Amaral Chapter 2 An Ontological Foundation for Understanding Multi-Paradigm Modeling for Cyber-Physical Systems R. Paige, M. van den Brand Chapter 3 Feature-based Survey of Cyber-Physical Systems B. Akesson, J. Hooman, R. Dekker, W. Ekkelkamp, B. Stottelaar PART II - Techniques Chapter 4 Current standards and best practices used in CPSG. Orhan & M. Aksit Chapter 5 Tools and techniques used in different disciplines for CPS development: Modeling languagesS. Schuster, I. Schaefer, C. Seidl Chapter 6 Tools and techniques used in different disciplines for CPS development: Interfaces for InteroperabilityO. Al-wadeai, A. García-Domínguez, A. Bagnato, A. Abhervé, K. Barmpis Chapter 7 Tools and techniques used in different disciplines for CPS development: ProcessesY. Luo, J. Mengerink, M. van den Brand, R. Schiffelers Chapter 8 Requirements for future MPM4CPS modelling tools and techniquesB. Tekinerdogan, D. Blouin PART III - Application Domains Chapter 9 Case Study: Alarm Detection and Monitoring of Smart Factory Environment using Hybrid Sensor Network L. Banjanovic-Mehmedovic, D. Blouin, F. Mehmedovic, M. Zukic Chapter 10 Case Study: Embedded Devices Constantin-Bala Zamfirescu and Peter Larsen Chapter 11 Case Study: SmartLab Cloud System for IoT H. Vangheluwe Chapter 12 Automated Analysis of Model-Driven Artifacts in Industry - Big Data Analytics Y. Luo, J. Mengerink, M. van den Brand, R. Schiffelers PART IV - Education Chapter 13 On a MPM4CPS CurriculaV. Amaral, M. Goulão Chapter 14Developing a mutually-recognized cross-domain study program in cyber-physical systems Paulo Carreira Glossary Author Index Subject Index