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Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.
- Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical field
- Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis
- Written by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic
Section I Overview of Single-Cell Omics1. Single-Cell Omics: An Overview2. Recent Progress in Single-Cell Sequencing3. Cellular Heterogeneity and Single-Cell Omics4. Single-Cell Omics: Cellular Functions5. Single-Cell Omics: Deciphering Tumor Clonal Architecture Section II Omics Technologies in Single-Cell6. An Overview of Single-Cell Isolation Techniques7. Microfluidic Techniques for Single-Cell Culture8. Single-Cell Omics in Noninvasive Diagnosis and Testing-Surface-Enhanced Raman Spectroscopy-Based Approach9. Single-Cell Genomics: Technology and Applications10. Single-Cell Metagenomics11. Single-Cell Epigenomics: Technology and Applications12. Single-Cell Transcriptomics: Technology and Applications13. Single-Cell Transcriptomics and Proteomics of Skeletal Muscle: Technology and Applications14. Single-Cell Proteomics: Technology and Applications15. Single-Cell Metabolomics: Technology and Applications16. Single-Cell Phenomics in Budding Yeast: Technologies and Applications17. Robotics in Single-Cell Omics18. Single-Cell Editing: The CRISPR/Cas9 and Applications Section III Data Analysis in Single-Cell Omics19. Data Analysis in Single-Cell RNA-Seq20. Systems-Level Understanding of Single-Cell Omics