The Immune System and Mental Health

The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson's and Alzheimer's-like dementia are explored.

Hymie Anisman received his PhD from the University of Waterloo, where he was also on faculty for two years, and has been a Professor at Carleton University, since 1994. He has also held an adjunct appointment with the Institute of Mental Health Research (Royal Ottawa Hospital) since 1993. Professor Anisman was a Senior Ontario Mental Health Research Fellow, is a Fellow of the Royal Society of Canada, and held a Canada Research Chair in Neuroscience from 2001-2015, and has since held the position of Canada Research Professor. The principle theme of his research has concerned the influence of stressors on neurochemical, neuroendocrine and immune systems, and how these influence psychological (anxiety, depression) and physical illnesses including neurodegenerative, heart disease, and cancer progression.

1. Multiple Pathways Linked to Mental Health and Illness2. The Immune System: An Overview3. Bacteria, Viruses, and the Microbiome4. Life-Style Factors Affecting Biological Processes and Health 5. Stressor Processes and Effects on Neurobiological Functioning6. Stress and Immunity7. Prenatal and Early Postnatal Influences on Health8. Depressive Disorders9. Anxiety Disorders10. Posttraumatic Stress Disorder11. Pain Processes12. Autism13. Schizophrenia14. Inflammatory Roads to Parkinson's Disease15. A Neuroinflammatory View of Alzheimer's Disease16. Comorbidities in Relation to Inflammatory processes