Exercise and Sport Pharmacology

Exercise and Sport Pharmacology is an essential book for teaching upper-level undergraduates or entry-level graduate students about how drugs can affect exercise and how exercise can affect the action of drugs. It leads students through the related pathology, exercise physiology, and drug action of many of today's chronically used medications, and discusses how drugs can affect exercise performance. This new second edition of the book is divided into four parts: Section I provides the basics of pharmacology, exercise physiology, autonomic pharmacology, and the stress response; Section II presents chapters on major cardiovascular and respiratory drug classes; Section III describes frequently prescribed medications for such common conditions as diabetes, depression, pain, fever, inflammation, and obesity; and Section IV includes discussions of nutritional supplements and commonly used drugs such as caffeine, nicotine, cannabis, and performance-enhancing drugs. The second edition offers many updates, enhances muscle cell physiology, includes the involvement of the gut microbiome, and each chapter has a new section on the effects of aging. In Sections II and III, chapters include an overview of the pathology that therapeutic drugs are designed to treat and how the drug works in the human body. In contrast to standard pharmacology texts, Exercise and Sport Pharmacology also includes the effect of exercise on the pathology of the condition and the effect of exercise on how the body responds to a drug. Each chapter has a section on whether the drugs under discussion have performance-enhancing potential. Section IV is concerned with self-medication and drugs or supplements taken without a prescription or with limited medical supervision. Throughout, figures and tables as well as data from experiments in exercise pharmacology help to illustrate and summarize content. Each chapter opens with an on-going case example to preview and apply chapter content. In the text, boldface terms indicate which concepts are contained in the book's Glossary. Chapters conclude with a Key Concepts Review and Review Questions.

Mark D. Mamrack Ph.D. is an emeritus faculty member and former Associate Dean at Wright State University in Dayton, Ohio. In over three decades at Wright State University, his research focused on cell signaling and growth control. He taught classes in cell and molecular biology and began teaching exercise pharmacology in 2002. That experience led to the creation of this text, Exercise and Sport Pharmacology, first published in 2015. This second edition expands and enhances content while maintaining the overall structure of the first edition.

Section I: Introduction 1. Basic Pharmacology 2. Basics of Exercise Performance 3. Autonomic Pharmacology and Stress Section II: Cardiovascular and Respiratory Drugs 4. Beta-blockers and Cardiovascular Disease 5. Cardiovascular Drugs and Hypertension 6. Diuretics 7. Respiratory Agents 8. Sympathomimetics Section III: Frequently Prescribed Medications 9. Psychotherapeutic Agents 10. Lipid-Modifying Agents 11. Analgesics and Anti-Inflammatory Drugs 12. Antidiabetic and Antiobesity Drugs Section IV: Self-Medication 13. Dietary Supplements 14. Caffeine 15. Ethanol, Nicotine, and Cannabis 16. Performance Enhancing Substances