Nutraceuticals and Cancer

This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.

Preface.-1. Global Overview of the Role of Nutraceuticals in Cancer.-2. Cancer Stem Cells: Novel Target Using Dietary Components for Prevention and Treatment.-3. Polyphenols as Receptor Tyrosine Kinase Inhibitors and Anti-Cancer Agents.-4. Role of Nutraceuticals on Nrf2 and Its Implication in Cancer Prevention.-5. Current Status and Future Prospects of Nutraceuticals in Prostate Cancer.-6. Cellular, Molecular and Biological Insight Into Chemopreventive and Therapeutic Potential Of 3, 3'-Diindolylmethane (Dim).-7. Mechanism of Action of the Anti-Cancer Agent, Triptolide.-8. Nutraceuticals in Human Urinary Bladder Cancer Prevention andTreatment.-9. Exploiting resveratrol for the treatment of cancer.-10. Role of novel nutraceuticals garcinol, plumbagin and mangiferin in the prevention and therapy of human malignancies: mechanisms of anticancer activity.-11. Anthocyanins and Cancer Prevention.-12. Slow but Steady Progress in Cancer Chemoprevention with Phenethyl isothiocyanate: Fulfilled Promises and Translational Challenges.-13. Skin cancer chemoprevention: Current status and future potential.-14. Dietary Phytochemicals and Chemoprevention of Solar Ultraviolet Radiation-Induced Skin Cancer.-15. The Role of Vitamin E Forms in Cancer Prevention and Therapy - Studies in Human Intervention Trials and Animal Models.-16. Augmenting the efficacy of chemo- and radio-therapy by nutraceuticals: Evidence from pre-clinical and clinical trials. Index.